{"id":"W2967709847","doi":"10.3389/fmars.2019.00533","title":"Transcriptome Analysis Reveals That Naphthenic Acids Perturb Gene Networks Related to Metabolic Processes, Membrane Integrity, and Gut Function in Silurana (Xenopus) tropicalis Embryos","year":2019,"lang":"en","type":"article","venue":"Frontiers in Marine Science","topic":"Petroleum Processing and Analysis","field":"Chemistry","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Environment and Climate Change Canada; Institut National de la Recherche Scientifique; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Environment and Climate Change Canada; University of Ottawa","keywords":"Transcriptome; Biology; Microarray analysis techniques; Microarray; Embryo; KEGG; Biochemistry; Cell biology; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006159249,0.0002516305,0.0002622798,0.0002043878,0.0001843111,0.0002301481,0.00009301705,0.0001449315,0.001052843],"category_scores_gemma":[0.00007247426,0.0001168772,0.0003949781,0.0001867211,0.0001197213,0.0001491291,0.0001849402,0.0003257208,0.0001630315],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002313968,"about_ca_system_score_gemma":0.0001944262,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00209295,"about_ca_topic_score_gemma":0.002834545,"domain_scores_codex":[0.9999131,0.000006978762,0.000005703434,0.00003489381,0.00002215616,0.00001708501],"domain_scores_gemma":[0.9999455,0.00001021489,0.00001999559,0.000002975658,0.0000102496,0.00001098998],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000736724,0.000005658938,0.0007888217,0.00004504118,0.000008188172,0.00005216006,0.0000207243,0.0000967498,0.9979891,0.00002880939,0.00003270437,0.0008583668],"study_design_scores_gemma":[0.00002246058,0.0005911929,0.283125,0.00003420802,0.0001355271,0.000557931,0.0003721807,0.003691474,0.7062514,0.0001479842,0.005045098,0.000025405],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922352,0.001195179,0.001841091,0.00008240758,0.00001367528,0.00001731049,0.003306556,0.00006082383,0.001247487],"genre_scores_gemma":[0.9864818,0.001444446,0.002854807,0.0001537654,0.000008249373,0.00007480205,0.004637423,0.0000317912,0.004312886],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00209295,"threshold_uncertainty_score":0.004161537,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006883025031828061,"score_gpt":0.224511245353283,"score_spread":0.2176282203214549,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}