{"id":"W2967709847","doi":"10.3389/fmars.2019.00533","title":"Transcriptome Analysis Reveals That Naphthenic Acids Perturb Gene Networks Related to Metabolic Processes, Membrane Integrity, and Gut Function in Silurana (Xenopus) tropicalis Embryos","year":2019,"lang":"en","type":"article","venue":"Frontiers in Marine Science","topic":"Petroleum Processing and Analysis","field":"Chemistry","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Environment and Climate Change Canada; Institut National de la Recherche Scientifique; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Environment and Climate Change Canada; University of Ottawa","keywords":"Transcriptome; Biology; Microarray analysis techniques; Microarray; Embryo; KEGG; Biochemistry; Cell biology; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001000339,0.000325494,0.0008485799,0.001402474,0.0001581619,0.0002134984,0.0007723829,0.0002092124,0.0002383212],"category_scores_gemma":[0.0002521893,0.0002862042,0.000149636,0.007873009,0.0002837618,0.0006043956,0.0002075056,0.0007090157,0.000005042157],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000175713,"about_ca_system_score_gemma":0.000166477,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003882103,"about_ca_topic_score_gemma":0.0001580579,"domain_scores_codex":[0.996946,0.00006671267,0.0005622637,0.001077822,0.0006595881,0.0006875871],"domain_scores_gemma":[0.9988441,0.00004714746,0.0001601421,0.0005635391,0.0001417157,0.0002433355],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000129287,0.00008145772,0.8834962,0.0001287657,0.0002015011,0.00000877426,0.0004195412,0.00403525,0.0979393,0.00003354178,0.00003570574,0.01349067],"study_design_scores_gemma":[0.005356998,0.0002162297,0.7295017,0.0005851433,0.002857351,0.0000476191,0.003628643,0.2205782,0.02705119,0.003129953,0.004290172,0.002756868],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925183,0.001385161,0.002890553,0.0003780507,0.0002217953,0.00006011875,0.000008520069,0.00007188219,0.002465627],"genre_scores_gemma":[0.9882069,0.00053383,0.004896614,0.0001713784,0.00003329947,0.00002091653,0.0000370674,0.00002100528,0.006078979],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2165429,"threshold_uncertainty_score":0.999959,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006883025031828061,"score_gpt":0.224511245353283,"score_spread":0.2176282203214549,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}