{"id":"W2967768556","doi":"10.3390/cells9020301","title":"Bezafibrate Improves Mitochondrial Fission and Function in DNM1L-Deficient Patient Cells","year":2020,"lang":"en","type":"article","venue":"Cells","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Hebrew University of Jerusalem","keywords":"Bezafibrate; Mitochondrial fission; DNM1L; Fission; Function (biology); Chemistry; Cell biology; Medicine; Biology; Physics; Internal medicine; Nuclear physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001841823,0.0004222902,0.0008685332,0.0003360946,0.0002227861,0.0002479349,0.0002550188,0.0004536028,0.001097485],"category_scores_gemma":[0.0002830094,0.00009730358,0.0003768016,0.0002027612,0.0001364672,0.0002311295,0.0002373181,0.0007011824,0.0002797385],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002456944,"about_ca_system_score_gemma":0.0001800859,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007940358,"about_ca_topic_score_gemma":0.0009569979,"domain_scores_codex":[0.9998806,0.00001997984,0.00002463391,0.00002506765,0.00002727274,0.0000224516],"domain_scores_gemma":[0.9998558,0.00002842997,0.00002929649,0.00001415781,0.00002144726,0.0000509075],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005047617,0.0006998277,0.001307066,0.0001723357,0.00006048386,0.001050495,0.00006675679,0.0002012199,0.9718164,0.00007384914,0.0004249198,0.01907904],"study_design_scores_gemma":[0.002107273,0.014239,0.02904683,0.00006501286,0.0003246278,0.00635255,0.0002592961,0.002973569,0.9269734,0.0003689769,0.01724587,0.0000435715],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939122,0.003639287,0.0008186832,0.0002820192,0.00006241627,0.0000314717,0.0003610809,0.0001207614,0.000772035],"genre_scores_gemma":[0.9959466,0.001326921,0.0009674937,0.0001769214,0.00001833636,0.0000205361,0.0006111655,0.00002315248,0.0009089776],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001097485,"threshold_uncertainty_score":0.003671408,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008585070584119885,"score_gpt":0.2005888661288074,"score_spread":0.1920037955446875,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}