{"id":"W2967826356","doi":"10.3389/fneur.2019.00935","title":"MEIS1 and Restless Legs Syndrome: A Comprehensive Review","year":2019,"lang":"en","type":"review","venue":"Frontiers in Neurology","topic":"Restless Legs Syndrome Research","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Genome-wide association study; Biology; Genetics; Enhancer; Homeobox; Restless legs syndrome; Genetic association; Gene; Candidate gene; Single-nucleotide polymorphism; Neuroscience; Transcription factor; Genotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0004610677,0.0006975094,0.006487486,0.001094547,0.00004298966,0.00002284331,0.0005218525,0.0008968428,0.00009186483],"category_scores_gemma":[0.0003014157,0.0005798353,0.0004572649,0.0008941024,0.0004517656,0.00007627589,0.0004497385,0.002648159,0.0002556616],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001315191,"about_ca_system_score_gemma":0.0006335194,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000250535,"about_ca_topic_score_gemma":0.000001630643,"domain_scores_codex":[0.9950548,0.001180245,0.001086313,0.001283804,0.0005141767,0.0008806551],"domain_scores_gemma":[0.9974695,0.000421989,0.000365395,0.001332098,0.0001068436,0.0003042129],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007201027,0.00009118142,0.0008299411,0.3843363,0.0003151124,0.008492778,0.00001050213,2.332993e-7,1.832291e-7,0.00003386928,0.0689353,0.5368826],"study_design_scores_gemma":[0.0007380976,0.0006358298,0.0005695767,0.04717895,0.0009289518,0.01758913,0.000002911314,0.00001138638,2.668025e-8,0.00002847236,0.9319733,0.000343391],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009912689,0.9919872,0.00001435169,0.001306749,0.001297564,0.004355464,0.00003089118,0.00005282751,0.0008558746],"genre_scores_gemma":[0.000004388326,0.9963163,0.0003817815,0.001450819,0.00007018998,0.0003262556,0.0001260069,0.0001630256,0.001161217],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.863038,"threshold_uncertainty_score":0.9996653,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1018200089338491,"score_gpt":0.3990606094421116,"score_spread":0.2972406005082626,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}