{"id":"W2967858406","doi":"10.3390/inorganics7080099","title":"Preliminary Characterization of a Ni2+-Activated and Mycothiol-Dependent Glyoxalase I Enzyme from Streptomyces coelicolor","year":2019,"lang":"en","type":"article","venue":"Inorganics","topic":"Advanced Glycation End Products research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada; University of Waterloo; McMaster University","keywords":"Lactoylglutathione lyase; Streptomyces coelicolor; Glutathione; Biochemistry; Enzyme; Intracellular; Methylglyoxal; Leishmania; Cysteine; Corynebacterium glutamicum; Thiol; Chemistry; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009395595,0.0004316605,0.0002906157,0.0002222946,0.0001267703,0.0002969344,0.0001874782,0.0001795828,0.0005583863],"category_scores_gemma":[0.0002407466,0.00006409422,0.0002935077,0.0003459064,0.0001256371,0.0001467662,0.0001639635,0.0003242482,0.0004017824],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001755185,"about_ca_system_score_gemma":0.0002700573,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002431639,"about_ca_topic_score_gemma":0.002004713,"domain_scores_codex":[0.9998634,0.00002766531,0.00001713124,0.00002329846,0.00003568438,0.00003283173],"domain_scores_gemma":[0.9998465,0.00002654989,0.00002893591,0.00001969242,0.00003389105,0.0000444969],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009267886,0.00003669562,0.0006242025,0.00005511707,0.000008183925,0.0001522589,0.00004317335,0.00008637748,0.9970235,0.00003479596,0.00002766791,0.001815237],"study_design_scores_gemma":[0.000009390175,0.0002988875,0.02023079,0.000007922114,0.00002643723,0.0006291668,0.0001174252,0.000553666,0.973529,0.00003913032,0.004546007,0.00001224614],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9867786,0.002043581,0.006282289,0.0001479988,0.00002231799,0.00007573515,0.001708122,0.00009114674,0.002850177],"genre_scores_gemma":[0.9774485,0.001228349,0.008383562,0.00006106644,0.00001502506,0.00003160746,0.008704283,0.00005365566,0.004073882],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002431639,"threshold_uncertainty_score":0.00483495,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007785513051774971,"score_gpt":0.2487014008215802,"score_spread":0.2409158877698052,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}