{"id":"W2967929847","doi":"10.1016/j.cellimm.2019.103963","title":"Conjugated CAR T cell one step beyond conventional CAR T cell for a promising cancer immunotherapy","year":2019,"lang":"en","type":"review","venue":"Cellular Immunology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"University of Tabriz; Tehran University of Medical Sciences and Health Services; Tabriz University of Medical Sciences; Northeastern States Research Cooperative","keywords":"Chimeric antigen receptor; Immunotherapy; Immune system; Cancer immunotherapy; Cancer research; T cell; Cancer; Biology; Cell; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0008094116,0.001087298,0.004452707,0.0007004697,0.0001942861,0.00007965133,0.0008078052,0.001664276,0.005983628],"category_scores_gemma":[0.00003918188,0.001022833,0.001896294,0.0005418955,0.000516323,0.00008307359,0.0002173293,0.001833157,0.0004793714],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001200507,"about_ca_system_score_gemma":0.003075465,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002408385,"about_ca_topic_score_gemma":0.000007393066,"domain_scores_codex":[0.994411,0.0006254692,0.00152819,0.001399862,0.0006093562,0.001426126],"domain_scores_gemma":[0.9960875,0.0005624826,0.0008963693,0.001708293,0.000537269,0.0002080882],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0015647,0.001104243,0.00001285479,0.04896527,0.005358633,0.0001341406,0.000259407,0.000001440725,0.4434066,0.0002276503,0.001629627,0.4973354],"study_design_scores_gemma":[0.007962699,0.001140977,0.000002022857,0.003960686,0.002178443,0.00009966436,0.00005225947,0.0000328889,0.0186616,0.00003565302,0.9650257,0.0008474343],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000756672,0.9851749,0.0003564447,0.0001213427,0.001805067,0.009179041,0.0003731865,0.0001971721,0.002036166],"genre_scores_gemma":[0.00006340639,0.9189506,0.0005391788,0.0001394434,0.0005993348,0.001505945,0.002585473,0.0006272143,0.07498941],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.963396,"threshold_uncertainty_score":0.9996318,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06636408974079762,"score_gpt":0.3527781913811653,"score_spread":0.2864141016403677,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}