{"id":"W2967994774","doi":"10.1016/j.jaci.2019.06.047","title":"Crisaborole and atopic dermatitis skin biomarkers: An intrapatient randomized trial","year":2019,"lang":"en","type":"article","venue":"Journal of Allergy and Clinical Immunology","topic":"Dermatology and Skin Diseases","field":"Medicine","cited_by":124,"is_retracted":false,"has_abstract":false,"ca_institutions":"Innovaderm (Canada)","funders":"Janssen Biotech; LEO Pharma; Glenmark Pharmaceuticals; Dermira; AbbVie; Celgene; Regeneron Pharmaceuticals; Novartis; European Commission; Pfizer; Kyowa Hakko Kirin; Galderma; Asana Biosciences; Eli Lilly and Company","keywords":"Atopic dermatitis; Randomized controlled trial; Dermatology; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000674396,0.0001163248,0.0009748216,0.000098319,0.00004303954,0.00001294958,0.00008164506,0.0002786117,0.0003109642],"category_scores_gemma":[0.0005812874,0.00008109008,0.0002361149,0.0000433013,0.0006481081,0.0001431849,0.00004221543,0.0003535147,0.00001081249],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007544068,"about_ca_system_score_gemma":0.00009484655,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008647098,"about_ca_topic_score_gemma":0.000006164626,"domain_scores_codex":[0.997946,0.0006387809,0.001011248,0.0001493601,0.0001009982,0.0001535596],"domain_scores_gemma":[0.9982809,0.0008763376,0.0004015456,0.000163572,0.000119573,0.0001581126],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.928206,0.001274867,0.0231247,0.00004519269,0.007321703,0.0003159071,0.0003909883,4.743466e-7,0.00007346638,0.001052529,0.002431484,0.03576275],"study_design_scores_gemma":[0.8191038,0.003256705,0.1657491,0.0001092711,0.0003828094,0.001664546,0.0003763377,0.0001076412,0.00004820613,0.001859191,0.007224019,0.0001183324],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9897173,0.006423858,0.00003280632,0.00185999,0.001205529,0.0002626627,0.000001101285,0.000008099269,0.0004886346],"genre_scores_gemma":[0.9881736,0.009971773,0.0003098952,0.00121178,0.0002189615,0.000003382577,0.000004782282,0.000007713292,0.00009811558],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1426244,"threshold_uncertainty_score":0.3404839,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01498015261926038,"score_gpt":0.3196916101071637,"score_spread":0.3047114574879033,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}