{"id":"W2968074771","doi":"10.1039/c9pp00142e","title":"Neutral iridium(III) complexes bearing BODIPY-substituted N-heterocyclic carbene (NHC) ligands: synthesis, photophysics, in vitro theranostic photodynamic therapy, and antimicrobial activity†","year":2019,"lang":"en","type":"article","venue":"Photochemical & Photobiological Sciences","topic":"Nanoplatforms for cancer theranostics","field":"Engineering","cited_by":44,"is_retracted":false,"has_abstract":false,"ca_institutions":"Acadia University","funders":"University of North Carolina at Greensboro; Natural Sciences and Engineering Research Council of Canada; Nova Scotia Research Innovation Trust; Acadia University; National Cancer Institute; National Science Foundation","keywords":"Carbene; Iridium; Antimicrobial; BODIPY; Photodynamic therapy; Chemistry; In vitro; Photosensitizer; Combinatorial chemistry; Bearing (navigation); Photochemistry; Medicinal chemistry; Organic chemistry; Biochemistry; Fluorescence; Catalysis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001773666,0.0002793342,0.0001880338,0.00009327712,0.000136371,0.0002729912,0.0003612102,0.0003346584,0.00090161],"category_scores_gemma":[0.0001777036,0.0001106792,0.00008118775,0.0001131102,0.0002509177,0.0002395313,0.0001515216,0.0003074038,0.0002402996],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004619609,"about_ca_system_score_gemma":0.0002029759,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006851021,"about_ca_topic_score_gemma":0.001173093,"domain_scores_codex":[0.9999156,0.000009809883,0.000005627531,0.00002240866,0.00002228327,0.00002425195],"domain_scores_gemma":[0.9999328,0.00001588303,0.00001628991,0.000006429834,0.00001264546,0.00001593881],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001212504,0.00001274922,0.00004491313,0.00006533133,0.00000261333,0.00002909255,0.00001239965,0.00008159022,0.9969549,0.0002513472,0.000114292,0.002309515],"study_design_scores_gemma":[0.000009954295,0.00008813413,0.0002105945,0.000002028196,0.000004564298,0.00006853192,0.000004093065,0.0002685237,0.9979919,0.00001773236,0.001330075,0.000003903697],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9749004,0.005590202,0.01121404,0.0002287936,0.00008119366,0.00008857388,0.0002627926,0.0002442676,0.007389775],"genre_scores_gemma":[0.9911363,0.001310614,0.004003939,0.00009699739,0.00001429265,0.00002787986,0.0002082097,0.00002725617,0.003174521],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00090161,"threshold_uncertainty_score":0.003351808,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01642596318351128,"score_gpt":0.2284357025958692,"score_spread":0.2120097394123579,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}