{"id":"W2968074771","doi":"10.1039/c9pp00142e","title":"Neutral iridium(III) complexes bearing BODIPY-substituted N-heterocyclic carbene (NHC) ligands: synthesis, photophysics, in vitro theranostic photodynamic therapy, and antimicrobial activity†","year":2019,"lang":"en","type":"article","venue":"Photochemical & Photobiological Sciences","topic":"Nanoplatforms for cancer theranostics","field":"Engineering","cited_by":44,"is_retracted":false,"has_abstract":false,"ca_institutions":"Acadia University","funders":"University of North Carolina at Greensboro; Natural Sciences and Engineering Research Council of Canada; Nova Scotia Research Innovation Trust; Acadia University; National Cancer Institute; National Science Foundation","keywords":"Carbene; Iridium; Antimicrobial; BODIPY; Photodynamic therapy; Chemistry; In vitro; Photosensitizer; Combinatorial chemistry; Bearing (navigation); Photochemistry; Medicinal chemistry; Organic chemistry; Biochemistry; Fluorescence; Catalysis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002763742,0.000600169,0.0008595351,0.0001688461,0.0001770216,0.0001788699,0.0007517142,0.0003257721,0.00009869569],"category_scores_gemma":[0.00005396973,0.0004660022,0.0001932425,0.0006193472,0.0007819585,0.0003778842,0.0001627096,0.0006015904,0.00002932608],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001909125,"about_ca_system_score_gemma":0.0000421556,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005016162,"about_ca_topic_score_gemma":0.0000601459,"domain_scores_codex":[0.9972402,0.00004477981,0.0005108193,0.0008996814,0.0002554923,0.001049051],"domain_scores_gemma":[0.9986945,0.0006104583,0.0001111981,0.0003461028,0.00003118765,0.000206504],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000351722,0.0001175354,0.0008707192,0.00004826426,0.0000440766,0.000008335718,0.0001173345,0.0006636115,0.9970011,0.00001660481,0.000008862843,0.0007518787],"study_design_scores_gemma":[0.001163604,0.0001224681,0.001602186,0.0001114679,0.0000173261,0.00002049836,0.00003271611,0.009030575,0.986677,0.0004740453,0.00008777305,0.0006603491],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968939,0.00046998,0.00003293268,0.00002887211,0.0003966645,0.001311585,0.00009758294,0.0003159981,0.000452524],"genre_scores_gemma":[0.9986566,0.0005759854,0.0002688679,0.0001621992,0.00008687986,0.0001786059,0.00002239091,0.00004284566,0.000005652022],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01032406,"threshold_uncertainty_score":0.9997792,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01642596318351128,"score_gpt":0.2284357025958692,"score_spread":0.2120097394123579,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}