{"id":"W2968099311","doi":"","title":"Transcription is required for active DNA demethylation","year":2007,"lang":"en","type":"article","venue":"Cancer Research","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"DNA demethylation; Biology; RNA polymerase II; Molecular biology; Chromatin; DNA methylation; Transcription (linguistics); Epigenetics of physical exercise; Histone methylation; Promoter; DNA; Genetics; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001495255,0.0002269237,0.0002388464,0.000203387,0.0001970984,0.0006166377,0.0002098335,0.0003687032,0.004182216],"category_scores_gemma":[0.0003438274,0.0002725025,0.0002901293,0.000111287,0.0002169049,0.0001885792,0.0002647089,0.0005467354,0.003138151],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007315515,"about_ca_system_score_gemma":0.0003599853,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001346788,"about_ca_topic_score_gemma":0.002337789,"domain_scores_codex":[0.99977,0.00002400857,0.00001936273,0.00007046815,0.00006740978,0.00004883589],"domain_scores_gemma":[0.9996895,0.00006899859,0.00006278775,0.00004390203,0.00005682618,0.00007805147],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001009272,0.00001622478,0.0003801725,0.00002399857,0.000002905258,0.000047684,0.00001340902,0.00002425186,0.99757,0.0001296629,0.0001743571,0.001516363],"study_design_scores_gemma":[0.00003841373,0.000183021,0.02402743,0.00002546184,0.00001006551,0.0003020201,0.00005970335,0.001581954,0.9601415,0.0002692454,0.01335216,0.000009003437],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9728675,0.005568274,0.007696609,0.0006387711,0.0002423036,0.00005537302,0.001887443,0.0007820106,0.01026171],"genre_scores_gemma":[0.9858167,0.0006722008,0.001792604,0.0001523319,0.00002776466,0.00002571543,0.003431484,0.00009511676,0.007986177],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004182216,"threshold_uncertainty_score":0.01399094,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1033241406513515,"score_gpt":0.436078306370745,"score_spread":0.3327541657193935,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}