{"id":"W2968123855","doi":"10.1186/s13072-019-0295-4","title":"ZFP57 regulation of transposable elements and gene expression within and beyond imprinted domains","year":2019,"lang":"en","type":"article","venue":"Epigenetics & Chromatin","topic":"Genetic Syndromes and Imprinting","field":"Biochemistry, Genetics and Molecular Biology","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Biotechnology and Biological Sciences Research Council; Medical Research Council; Wellcome Trust; Wellcome","keywords":"Biology; DNA methylation; Genomic imprinting; Genetics; Transposable element; Chromatin; Differentially methylated regions; Epigenetics; RNA-Directed DNA Methylation; Epigenomics; Regulation of gene expression; Epigenetics of physical exercise; Gene; Genome; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002128329,0.000160293,0.0001930923,0.00004326173,0.00005222056,0.00001893104,0.0000991722,0.0001278979,0.00004321823],"category_scores_gemma":[0.00002353973,0.0001558545,0.00003825615,0.00005937558,0.00006568324,0.000004406673,0.0001187691,0.00005208395,0.000003020396],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006022538,"about_ca_system_score_gemma":0.00002801517,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007188253,"about_ca_topic_score_gemma":0.000006682811,"domain_scores_codex":[0.9988707,0.00004720711,0.0003892791,0.0003464141,0.0001472634,0.0001991928],"domain_scores_gemma":[0.999347,0.00001203354,0.0001879581,0.0003207176,0.00005420822,0.00007812116],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001067439,0.00002604139,0.06697577,0.00007238369,0.0000247212,1.844286e-7,0.0001827838,0.00007474249,0.9313835,0.00003698632,0.0000186253,0.001193599],"study_design_scores_gemma":[0.000818193,0.0003223554,0.1321658,0.00004152981,0.00001788484,0.00001352495,0.0001121485,0.001256635,0.8646166,0.0001354878,0.0003410394,0.0001587401],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970958,0.0007620461,0.001126928,0.00002419857,0.00009497901,0.0003060591,0.00001491681,0.000007738636,0.0005672886],"genre_scores_gemma":[0.9629774,0.0002266161,0.03629152,0.00003308223,0.00003536265,0.000007419384,0.00005744238,0.00002551168,0.0003456564],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06676684,"threshold_uncertainty_score":0.635556,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004894203272541832,"score_gpt":0.2182736398448129,"score_spread":0.2133794365722711,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}