{"id":"W2968238024","doi":"10.1097/tp.0000000000002911","title":"Long-term Kinetics of Intragraft Gene Signatures in Renal Allograft Tolerance Induced by Transient Mixed Chimerism","year":2019,"lang":"en","type":"article","venue":"Transplantation","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Institute of Allergy and Infectious Diseases; National Heart, Lung, and Blood Institute","keywords":"FOXP3; Immunosuppression; Kidney; GATA3; Immunology; Medicine; Internal medicine; Renal function; Biology; Endocrinology; Immune system; Gene; Transcription factor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002378976,0.0001020454,0.000149107,0.0002574562,0.00007728638,0.0002476273,0.0001013209,0.000144016,0.0006447668],"category_scores_gemma":[0.0002500334,0.00007223939,0.0001188335,0.0001338297,0.0001580002,0.0001587438,0.0001360558,0.000280486,0.0001722211],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001652239,"about_ca_system_score_gemma":0.00008499256,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001722264,"about_ca_topic_score_gemma":0.0002480822,"domain_scores_codex":[0.9998879,0.00001318061,0.000007734019,0.00002592763,0.00003074159,0.00003438665],"domain_scores_gemma":[0.999756,0.00004110133,0.0001118857,0.00001783559,0.00002992122,0.0000431923],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001556632,0.00007711024,0.04737014,0.00004612928,0.00002583488,0.0001872683,0.0001116052,0.0001384052,0.9441765,0.00005312876,0.00004990752,0.006207196],"study_design_scores_gemma":[0.00003099512,0.002553612,0.5374802,0.00002045628,0.0001386964,0.001384108,0.000267964,0.001541745,0.4549909,0.00009007934,0.001487091,0.00001418076],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989267,0.0003513684,0.0003942048,0.000004743488,0.000002128768,0.00000495028,0.00008792296,0.000009306486,0.0002186774],"genre_scores_gemma":[0.9992012,0.0001131439,0.0001729325,0.000009748856,0.000002214527,0.00001764797,0.000219391,0.00000403608,0.0002595507],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006447668,"threshold_uncertainty_score":0.002156973,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01162835375126092,"score_gpt":0.2667410186162989,"score_spread":0.255112664865038,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}