{"id":"W2968251716","doi":"10.1101/lm.049965.119","title":"Polysomes identified by live imaging of nascent peptides are stalled in hippocampal and cortical neurites","year":2019,"lang":"en","type":"article","venue":"Learning & Memory","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Canadian Institutes of Health Research; McGill University","keywords":"Polysome; Puromycin; Cell biology; Neurite; Translation (biology); Hippocampal formation; Messenger RNA; Protein biosynthesis; RNA; Biology; Ribosome; Chemistry; Biophysics; Molecular biology; Biochemistry; Neuroscience; Gene; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000918377,0.0002169905,0.0001202103,0.0002883617,0.0002686733,0.0002557537,0.0002337417,0.0002531467,0.001674549],"category_scores_gemma":[0.00009392817,0.0001710782,0.000123137,0.0001695704,0.0002073903,0.0002419374,0.0002405803,0.0004992078,0.0003830635],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003741648,"about_ca_system_score_gemma":0.0002786264,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002834072,"about_ca_topic_score_gemma":0.004631331,"domain_scores_codex":[0.9999595,0.000001616726,0.000002283359,0.00001170079,0.00001384658,0.00001110291],"domain_scores_gemma":[0.9999136,0.0000181105,0.00001906343,0.000007920024,0.00001683512,0.00002445528],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004919312,0.000009626177,0.0003345572,0.00003387739,0.000002818114,0.00009763824,0.00004973351,0.00009023061,0.9976331,0.000194003,0.00005358585,0.00145148],"study_design_scores_gemma":[0.00002220426,0.0002006184,0.05346788,0.00003186601,0.00001710754,0.0006674799,0.0002172813,0.005812232,0.9364693,0.0004190819,0.002660227,0.00001475403],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.986392,0.0007852724,0.008367169,0.00008706006,0.00002360714,0.00002647818,0.0006898814,0.0001279269,0.003500571],"genre_scores_gemma":[0.9583443,0.001609858,0.02677325,0.0001040836,0.00002661398,0.0001186105,0.000952871,0.0001550939,0.01191532],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002834072,"threshold_uncertainty_score":0.005635142,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004626269518635606,"score_gpt":0.2420763345216639,"score_spread":0.2374500650030283,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}