{"id":"W2968251716","doi":"10.1101/lm.049965.119","title":"Polysomes identified by live imaging of nascent peptides are stalled in hippocampal and cortical neurites","year":2019,"lang":"en","type":"article","venue":"Learning & Memory","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Canadian Institutes of Health Research; McGill University","keywords":"Polysome; Puromycin; Cell biology; Neurite; Translation (biology); Hippocampal formation; Messenger RNA; Protein biosynthesis; RNA; Biology; Ribosome; Chemistry; Biophysics; Molecular biology; Biochemistry; Neuroscience; Gene; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002516252,0.00009751535,0.0001664734,0.00005456425,0.00004154444,0.00002744892,0.00009429547,0.00004675625,0.00003718817],"category_scores_gemma":[0.0002685014,0.00009447868,0.00004327401,0.00005032322,0.00007917247,0.000006519527,0.0001203779,0.0002213254,0.00001041384],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009059814,"about_ca_system_score_gemma":0.00002492098,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009425161,"about_ca_topic_score_gemma":0.00002104053,"domain_scores_codex":[0.9990461,0.0001300955,0.0001689127,0.0002598207,0.0001467077,0.0002483628],"domain_scores_gemma":[0.999626,0.00005059397,0.00007110069,0.0001415746,0.00003654074,0.00007414258],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00006172197,0.0000204601,0.3668496,0.00003498541,0.000009891052,0.000005824177,0.00009385825,0.00005003657,0.6320083,0.00000152219,0.00009981699,0.0007640452],"study_design_scores_gemma":[0.002102755,0.0003351117,0.6225826,0.0001980024,0.00001457854,0.0000222179,0.004897305,0.002469669,0.3666167,0.00002125012,0.0003898097,0.0003500672],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975182,0.002051806,0.00002116098,0.0001040305,0.00003651224,0.0001231527,0.000002378122,0.000007604732,0.0001351907],"genre_scores_gemma":[0.9977235,0.0002081478,0.00005062743,0.00005600701,0.00002985473,0.000004365864,0.00002255766,0.0000150592,0.001889904],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2653916,"threshold_uncertainty_score":0.3852729,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004626269518635606,"score_gpt":0.2420763345216639,"score_spread":0.2374500650030283,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}