{"id":"W2968439743","doi":"10.1016/j.ajpath.2019.07.009","title":"The Inability of the Choroid to Revascularize in Oxygen-Induced Retinopathy Results from Increased p53/miR-Let-7b Activity","year":2019,"lang":"en","type":"article","venue":"American Journal Of Pathology","topic":"Retinopathy of Prematurity Studies","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Heart Institute; Centre Hospitalier Universitaire Sainte-Justine; McGill University; Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"Fonds de Recherche du Québec - Santé; Canadian Stroke Network; Canada Research Chairs; Heart and Stroke Foundation of Canada; Canadian Institutes of Health Research; March of Dimes Foundation","keywords":"Choroid; Retinopathy of prematurity; Retinal; Retina; Retinal pigment epithelium; Medicine; Hyperoxia; Insulin-like growth factor 1 receptor; Retinopathy; Choroidal neovascularization; Ophthalmology; Pathology; Endocrinology; Internal medicine; Biology; Receptor; Neuroscience; Growth factor; Genetics; Lung","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005015953,0.0003960074,0.000274184,0.000796366,0.0004405176,0.0005649535,0.0002682825,0.0005262824,0.002811744],"category_scores_gemma":[0.0006188328,0.0003541543,0.000451602,0.000291048,0.0005539324,0.0005285369,0.0003357676,0.001304651,0.0004132675],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004126698,"about_ca_system_score_gemma":0.0003609453,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001502713,"about_ca_topic_score_gemma":0.001140343,"domain_scores_codex":[0.9996779,0.00006327331,0.00003516968,0.0000613874,0.00009743806,0.00006481694],"domain_scores_gemma":[0.9995174,0.0000985787,0.0001725059,0.0000820214,0.00004648235,0.00008291072],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007336785,0.0001530377,0.003831816,0.00007869874,0.0000367744,0.0008824173,0.00008954953,0.0000549423,0.9901555,0.000731923,0.0001476104,0.003104029],"study_design_scores_gemma":[0.00003998227,0.0004407428,0.05564958,0.00002314345,0.0001010454,0.00271799,0.0002383789,0.001198706,0.9367909,0.0004469975,0.002340234,0.00001242829],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990517,0.001395483,0.004376828,0.0002597998,0.00007083848,0.00004236402,0.0003038993,0.00009111076,0.0029426],"genre_scores_gemma":[0.9951002,0.0006256962,0.001950366,0.00006760278,0.00000976683,0.00004873701,0.000238627,0.00003058503,0.001928461],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002811744,"threshold_uncertainty_score":0.009406149,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01003375308200789,"score_gpt":0.2645245664909149,"score_spread":0.2544908134089071,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}