{"id":"W2968527376","doi":"10.1016/j.micinf.2019.08.002","title":"Ripk3 licenced protection against microbial infection in the absence of Caspase1-11 inflammasome","year":2019,"lang":"en","type":"article","venue":"Microbes and Infection","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Pyroptosis; Inflammasome; Necroptosis; Phagosome; Innate immune system; Salmonella; Programmed cell death; AIM2; Biology; Inflammation; Microbiology; Salmonella enterica; Caspase 1; Immune system; Immunology; Apoptosis; Bacteria; Phagocytosis; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002313013,0.0001253325,0.0001147857,0.00009164411,0.00007446471,0.00002747003,0.000056152,0.0001451501,0.00001243392],"category_scores_gemma":[0.00002581697,0.0001037672,0.00006624309,0.0001775272,0.00005751831,0.00002198504,0.00004092938,0.0001155312,0.00001128994],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001450386,"about_ca_system_score_gemma":0.00002572444,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001536231,"about_ca_topic_score_gemma":0.001862429,"domain_scores_codex":[0.9992695,0.00007802949,0.000219991,0.0002158072,0.00005765541,0.0001590214],"domain_scores_gemma":[0.9996228,0.000005632608,0.0001115939,0.0001869627,0.00005977047,0.00001324691],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004583898,0.00004910496,0.09003741,0.00005216174,0.00001023769,2.732143e-7,0.0001948055,0.00018965,0.9067381,0.00002202248,0.00009783924,0.00256252],"study_design_scores_gemma":[0.0009933698,0.0004710746,0.2686617,0.00006474266,0.000009242201,0.00003122004,0.0001167325,0.0001137554,0.7003172,0.00002289326,0.02897738,0.0002207004],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99838,0.0001412073,0.000182908,0.00005294038,0.0002223562,0.0004650209,0.000002834924,0.000008476701,0.0005442568],"genre_scores_gemma":[0.9987609,0.0008371885,0.00001672171,0.0001083241,0.00007576102,0.00002831203,0.00005094089,0.00001005652,0.0001117836],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.206421,"threshold_uncertainty_score":0.4231502,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004801997218789208,"score_gpt":0.2026625463754453,"score_spread":0.1978605491566561,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}