{"id":"W2968527376","doi":"10.1016/j.micinf.2019.08.002","title":"Ripk3 licenced protection against microbial infection in the absence of Caspase1-11 inflammasome","year":2019,"lang":"en","type":"article","venue":"Microbes and Infection","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Pyroptosis; Inflammasome; Necroptosis; Phagosome; Innate immune system; Salmonella; Programmed cell death; AIM2; Biology; Inflammation; Microbiology; Salmonella enterica; Caspase 1; Immune system; Immunology; Apoptosis; Bacteria; Phagocytosis; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003891041,0.0006086645,0.0008794256,0.0004955865,0.000282761,0.0007441406,0.0003896275,0.000815849,0.008569662],"category_scores_gemma":[0.0004387504,0.000286745,0.0005148813,0.0003655567,0.0007975962,0.0006546754,0.0003845471,0.003168833,0.001537465],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000374178,"about_ca_system_score_gemma":0.0006828838,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006624101,"about_ca_topic_score_gemma":0.0007209167,"domain_scores_codex":[0.999385,0.00008487365,0.00006876989,0.00009902864,0.0001170527,0.0002451665],"domain_scores_gemma":[0.9996827,0.00005245617,0.0000495676,0.00006928396,0.00003561643,0.0001103726],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003744965,0.0002969438,0.0001640863,0.0001264155,0.00002007563,0.0001564074,0.00002812605,0.0001071346,0.9929371,0.00030812,0.000383786,0.001726753],"study_design_scores_gemma":[0.0003572239,0.002068159,0.003479268,0.00002012339,0.00005533047,0.0006393262,0.0001084379,0.001307154,0.9862766,0.0003198158,0.005346057,0.00002248133],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9870121,0.002853389,0.002628105,0.0007091165,0.0006680524,0.00008019982,0.002150857,0.0003493401,0.003548873],"genre_scores_gemma":[0.9903731,0.0009172644,0.001229014,0.0002488988,0.00005705922,0.0001088141,0.001310335,0.00004861599,0.005706907],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008569662,"threshold_uncertainty_score":0.02866834,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004801997218789208,"score_gpt":0.2026625463754453,"score_spread":0.1978605491566561,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}