{"id":"W2968592991","doi":"10.1055/s-0037-1611907","title":"Metal-Catalyzed Site-Selective Monoacylation of Diols in Aqueous Media","year":2019,"lang":"en","type":"article","venue":"Synthesis","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Acylation; Metal ions in aqueous solution; Reagent; Chelation; Phosphate; Aqueous solution; Organic chemistry; Combinatorial chemistry; Diol; Metal; Inorganic chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001901089,0.0001162737,0.0002804057,0.00007168381,0.00001221659,0.000006040441,0.0001247643,0.000123389,0.0001429013],"category_scores_gemma":[0.0005194708,0.0001030533,0.0001697064,0.0001807086,0.00003293086,0.000004258112,0.00005125775,0.00004767324,0.00004219221],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001819283,"about_ca_system_score_gemma":0.00002272151,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001057427,"about_ca_topic_score_gemma":0.0000879928,"domain_scores_codex":[0.9991322,0.00006117756,0.0002380436,0.0002864317,0.0001210252,0.0001611765],"domain_scores_gemma":[0.9993899,0.0001454173,0.0001016049,0.0002780226,0.00004426394,0.00004072877],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005068373,0.00005927583,0.01727057,0.00001274544,0.00007376271,5.383357e-7,0.00004429615,0.0000414296,0.9689704,0.00001337706,0.00002888409,0.01343408],"study_design_scores_gemma":[0.0001370142,0.00001502229,0.008619107,0.00001886606,0.0000489072,8.168673e-7,0.00004500911,0.0001876918,0.990222,0.00009254719,0.0004841769,0.000128806],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972332,0.0005907926,0.00007059397,0.00005847595,0.00002212688,0.00009820783,0.00002237221,0.000005458522,0.001898792],"genre_scores_gemma":[0.9994266,0.0001058573,0.0002396891,0.00001526859,0.00004426207,0.0000204255,0.00004589684,0.00001454956,0.00008741808],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02125167,"threshold_uncertainty_score":0.4202394,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00525241903348528,"score_gpt":0.2099723152190016,"score_spread":0.2047198961855164,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}