{"id":"W2968942240","doi":"10.1182/blood.2019000324","title":"Pembrolizumab in relapsed or refractory Hodgkin lymphoma: 2-year follow-up of KEYNOTE-087","year":2019,"lang":"en","type":"article","venue":"Blood","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":329,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital","funders":"National Cancer Institute","keywords":"Pembrolizumab; Medicine; Refractory (planetary science); Lymphoma; Internal medicine; Oncology; Hodgkin lymphoma; Cancer; Immunotherapy; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000144546,0.0002071098,0.0005563865,0.0001683833,0.00002263637,0.000008837976,0.0001100405,0.0001669232,0.0005154206],"category_scores_gemma":[0.0001141731,0.0001517481,0.0001667223,0.0002585969,0.0000369551,0.00005455761,0.00005802069,0.00007442479,0.0003473636],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001570264,"about_ca_system_score_gemma":0.0003281946,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003185599,"about_ca_topic_score_gemma":0.00008305148,"domain_scores_codex":[0.9985216,0.0000510881,0.0003933859,0.0003538167,0.0003396033,0.0003405291],"domain_scores_gemma":[0.998956,0.0001436644,0.0001358779,0.0005782475,0.00006509071,0.0001211664],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00513801,0.009648028,0.9661584,0.0003023146,0.000485057,0.0007155458,0.0007392837,0.000002139317,0.006107178,0.0005772448,0.00142675,0.008700015],"study_design_scores_gemma":[0.1530831,0.002961211,0.8077798,0.0004894765,0.0004543525,0.000129829,0.0002143923,0.0000148805,0.0299913,0.00005877736,0.004563566,0.000259323],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9895297,0.0006280101,5.306799e-7,0.0001665655,0.000244873,0.0005723116,0.0000174398,0.00004485161,0.008795692],"genre_scores_gemma":[0.9958994,0.0001560381,0.0002944947,0.000144328,0.00006912749,0.00005225232,0.00002757995,0.0000365566,0.00332026],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1583787,"threshold_uncertainty_score":0.6188109,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01353759303662356,"score_gpt":0.2492147533128331,"score_spread":0.2356771602762095,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}