{"id":"W2968979426","doi":"10.1093/noajnl/vdz014.022","title":"BSCI-26. COMPARATIVE METHYLATION PROFILING OF EGFR MUTANT LUNG ADENOCARCINOMA AND PAIRED BRAIN METASTASIS","year":2019,"lang":"en","type":"article","venue":"Neuro-Oncology Advances","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Brain metastasis; Lung cancer; CpG site; Metastasis; Cancer research; Adenocarcinoma; Biology; DNA methylation; Methylation; Lung; Oncology; Pathology; Medicine; Internal medicine; Gene; Cancer; Gene expression; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001655241,0.0001605588,0.000212081,0.0005975495,0.0002384546,0.0001895673,0.0001757411,0.0002254503,0.001582894],"category_scores_gemma":[0.0003270395,0.000127583,0.0001742864,0.0004080447,0.0001147304,0.00005538483,0.00022894,0.0001881692,0.0004221888],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002994721,"about_ca_system_score_gemma":0.0002251884,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003807557,"about_ca_topic_score_gemma":0.005597575,"domain_scores_codex":[0.9998319,0.00001624428,0.000009085475,0.00005340109,0.00006152223,0.00002780834],"domain_scores_gemma":[0.9998615,0.00001878773,0.00002393368,0.00001230274,0.00004937405,0.00003410139],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001035864,0.00003678903,0.04970734,0.00007468605,0.00005076082,0.0002387113,0.00007687401,0.0002024555,0.9394159,0.00004071432,0.0002444269,0.008875484],"study_design_scores_gemma":[0.00003405643,0.0007476091,0.6960033,0.000007864964,0.0001113637,0.002272234,0.0001102807,0.002583312,0.295842,0.00008586692,0.002190111,0.00001198782],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954339,0.0005571018,0.001436637,0.00001830253,0.000005973279,0.00002727322,0.001522217,0.0000619097,0.0009366125],"genre_scores_gemma":[0.9934705,0.000155504,0.001851333,0.00002086506,0.000002960565,0.00003938756,0.003416066,0.00002020156,0.001023152],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003807557,"threshold_uncertainty_score":0.007570744,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02141255484801181,"score_gpt":0.3148820644158687,"score_spread":0.2934695095678569,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}