{"id":"W2969089843","doi":"10.1016/bs.mie.2019.07.030","title":"Simplified high yield TAILS terminomics using a new HPG-ALD 800K-2000 polymer with precipitation","year":2019,"lang":"en","type":"article","venue":"Methods in enzymology on CD-ROM/Methods in enzymology","topic":"Advanced Proteomics Techniques and Applications","field":"Chemistry","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Proteome; Polymer; Mass spectrometry; Trypsin; Isotopic labeling; Peptide; Proteomics; Chromatography; Biochemistry; Enzyme; Organic chemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.002752418,0.0008287673,0.00155709,0.0007794068,0.0001532738,0.00004175202,0.001017135,0.001576467,0.00124212],"category_scores_gemma":[0.0009292644,0.0008353858,0.0001911902,0.0009087163,0.0004618322,0.0002240113,0.0003422622,0.002019976,0.00003687554],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007464554,"about_ca_system_score_gemma":0.0004743334,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001384663,"about_ca_topic_score_gemma":0.0003613549,"domain_scores_codex":[0.9934615,0.001719898,0.001488265,0.001782019,0.0002255935,0.001322648],"domain_scores_gemma":[0.9919524,0.005149642,0.0008013846,0.001757238,0.0001018608,0.0002375058],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008434309,0.0003900237,0.01178086,0.0000922874,0.00008550997,0.0000659042,0.0008412187,0.002795384,0.9031352,0.01601508,0.00007571452,0.0638794],"study_design_scores_gemma":[0.003552178,0.0008469918,0.009987553,0.0002952216,0.0001231338,0.0005806469,0.0004081258,0.001544668,0.8688365,0.1084388,0.003698304,0.001687874],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.562898,0.0002907483,0.4317138,0.0003536523,0.0003670972,0.0007891944,0.00002758005,0.0002043814,0.003355583],"genre_scores_gemma":[0.1110155,0.00006064818,0.8845376,0.0009827504,0.0002091484,0.0004383143,0.00004530504,0.0001681245,0.002542673],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.4528238,"threshold_uncertainty_score":0.9997197,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05067334878330765,"score_gpt":0.4047849838713775,"score_spread":0.3541116350880699,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}