{"id":"W2969101527","doi":"10.3389/fimmu.2019.02075","title":"Mucosal-Pull Induction of Lung-Resident Memory CD8 T Cells in Parenteral TB Vaccine-Primed Hosts Requires Cognate Antigens and CD4 T Cells","year":2019,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Immunology; CD8; Lung; Antigen; Immunization; Memory T cell; Cognate; Effector; Medicine; T cell; Biology; Immune system; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001735292,0.0004642668,0.0002734723,0.0001211588,0.0001165906,0.0003074952,0.0001741699,0.0004101852,0.001498259],"category_scores_gemma":[0.0001497503,0.0001311723,0.0002581924,0.00005980905,0.0002171445,0.0004149489,0.0003448599,0.001305248,0.0005391532],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000108075,"about_ca_system_score_gemma":0.0001421769,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008356645,"about_ca_topic_score_gemma":0.0002162752,"domain_scores_codex":[0.9998413,0.00002351877,0.00001191901,0.00004464374,0.00002276932,0.00005578435],"domain_scores_gemma":[0.9999123,0.00001889142,0.00002158905,0.00001623388,0.000007008644,0.00002394992],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001328728,0.00008316551,0.0002466878,0.00004987811,0.000002939677,0.00003335421,0.00002095155,0.00004619266,0.9960808,0.00008026572,0.0000412147,0.00318166],"study_design_scores_gemma":[0.00003102237,0.001796528,0.003473578,0.00001820828,0.00001758579,0.0002817531,0.00008721339,0.000880599,0.9913999,0.0001220167,0.001886822,0.000004935686],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925291,0.0007983195,0.004560309,0.0001445969,0.00005779672,0.00004768409,0.0001254091,0.0000935496,0.001643172],"genre_scores_gemma":[0.9922694,0.0003453521,0.004165285,0.000146721,0.0000254172,0.00005476143,0.0002373419,0.00003425628,0.002721374],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001498259,"threshold_uncertainty_score":0.005012155,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005472668741076305,"score_gpt":0.2127785547927077,"score_spread":0.2073058860516314,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}