{"id":"W2969207313","doi":"10.1155/2019/8918914","title":"<i>Sargassum fusiforme</i> Fucoidan SP2 Extends the Lifespan of <i>Drosophila melanogaster</i> by Upregulating the Nrf2-Mediated Antioxidant Signaling Pathway","year":2019,"lang":"en","type":"article","venue":"Oxidative Medicine and Cellular Longevity","topic":"Seaweed-derived Bioactive Compounds","field":"Agricultural and Biological Sciences","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Northern British Columbia","funders":"Wenzhou University; Natural Science Foundation of Shandong Province; National Natural Science Foundation of China","keywords":"Fucoidan; Drosophila melanogaster; Antioxidant; Sargassum; Cell biology; Signal transduction; Drosophila (subgenus); Biology; Chemistry; Biochemistry; Polysaccharide; Botany; Gene; Algae","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001244793,0.0003512228,0.000513695,0.00001969515,0.0004036769,0.00004817766,0.0005214196,0.0001201566,0.0003677618],"category_scores_gemma":[0.0001960605,0.0001046876,0.0001279379,0.0005309987,0.0007173167,0.0001790964,0.000239595,0.0003707819,0.00002105769],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002679518,"about_ca_system_score_gemma":0.0000164717,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003263658,"about_ca_topic_score_gemma":0.00006656106,"domain_scores_codex":[0.9975088,0.0004562042,0.0004821209,0.000515205,0.0005966931,0.0004409757],"domain_scores_gemma":[0.9976786,0.001300205,0.0004535075,0.0002331068,0.0001925639,0.0001420428],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005252693,0.00006638513,0.01566326,0.00002237788,0.00005596523,0.000003852915,0.0006502912,9.771005e-7,0.9755802,0.0001354237,0.0005344703,0.007234231],"study_design_scores_gemma":[0.001318205,0.001574149,0.105328,0.0003465502,0.0001551755,0.0000298242,0.01117974,0.0002742014,0.847869,0.0005882184,0.03070784,0.0006290098],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9906827,0.002067452,0.00004357861,0.004115932,0.0001916419,0.0005530033,0.00008402528,0.00004049752,0.002221221],"genre_scores_gemma":[0.9981495,0.0001248538,0.00001782042,0.0008075483,0.0004101364,0.00001526463,0.0001456515,0.000004778897,0.0003244292],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1277112,"threshold_uncertainty_score":0.4269038,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01732420501339817,"score_gpt":0.2094120763838027,"score_spread":0.1920878713704045,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}