{"id":"W2969207313","doi":"10.1155/2019/8918914","title":"<i>Sargassum fusiforme</i> Fucoidan SP2 Extends the Lifespan of <i>Drosophila melanogaster</i> by Upregulating the Nrf2-Mediated Antioxidant Signaling Pathway","year":2019,"lang":"en","type":"article","venue":"Oxidative Medicine and Cellular Longevity","topic":"Seaweed-derived Bioactive Compounds","field":"Agricultural and Biological Sciences","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Northern British Columbia","funders":"Wenzhou University; Natural Science Foundation of Shandong Province; National Natural Science Foundation of China","keywords":"Fucoidan; Drosophila melanogaster; Antioxidant; Sargassum; Cell biology; Signal transduction; Drosophila (subgenus); Biology; Chemistry; Biochemistry; Polysaccharide; Botany; Gene; Algae","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007081882,0.0003337748,0.0001495341,0.0001835849,0.0001095898,0.0001510133,0.0001135619,0.0001451616,0.0008887741],"category_scores_gemma":[0.00003919519,0.00007265875,0.0002471383,0.0001121721,0.00008635863,0.0001480546,0.0001304141,0.0003378989,0.0001402078],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002003761,"about_ca_system_score_gemma":0.00009080395,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009945707,"about_ca_topic_score_gemma":0.001696441,"domain_scores_codex":[0.9999576,0.000006906091,0.000004728559,0.00001016931,0.0000108542,0.000009799466],"domain_scores_gemma":[0.9999567,0.000003144155,0.00001589259,0.000004278062,0.000006841593,0.00001325473],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006006642,0.000008601817,0.0001157312,0.00002512215,0.000004869895,0.00001939881,0.000004270095,0.00001820168,0.9991849,0.0000198275,0.00002459223,0.0005143693],"study_design_scores_gemma":[0.0000144944,0.0004430644,0.01672825,0.00001070827,0.00002967827,0.0001997142,0.00004270892,0.0005849976,0.9774317,0.00003582116,0.004471381,0.000007493443],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961088,0.0009377903,0.001056157,0.00007350085,0.00001784566,0.00001600379,0.0005696237,0.00004199086,0.001178321],"genre_scores_gemma":[0.9941673,0.0005445792,0.001561162,0.00008901684,0.000006752462,0.00001846463,0.0009126476,0.00001496214,0.0026851],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009945707,"threshold_uncertainty_score":0.002973199,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01732420501339817,"score_gpt":0.2094120763838027,"score_spread":0.1920878713704045,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}