{"id":"W2969437842","doi":"10.1016/j.intimp.2019.105816","title":"Docosahexaenoic acid inhibits hepatic stellate cell activation to attenuate liver fibrosis in a PPARγ-dependent manner","year":2019,"lang":"en","type":"article","venue":"International Immunopharmacology","topic":"Liver Disease Diagnosis and Treatment","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Natural Science Foundation of China; Cultivating Plan Program for the Leader in Science and Technology of Yunnan Province; Ministry of Natural Resources","keywords":"Hepatic stellate cell; Docosahexaenoic acid; Peroxisome proliferator-activated receptor; Downregulation and upregulation; Hepatic fibrosis; Fibrosis; Receptor; Peroxisome; Viability assay; Cell biology; Chemistry; Biology; Cell; Pharmacology; Biochemistry; Cancer research; Internal medicine; Endocrinology; Polyunsaturated fatty acid; Fatty acid; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0001135888,0.0002051773,0.0002826732,0.0003390308,0.00002919192,0.00002884452,0.0001728087,0.00008594878,0.003388246],"category_scores_gemma":[0.00001539817,0.0001888304,0.0001065824,0.0001629373,0.00002016849,0.0001802985,0.000147311,0.0001837769,0.002828605],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005196584,"about_ca_system_score_gemma":0.00007650062,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002808773,"about_ca_topic_score_gemma":0.00001333347,"domain_scores_codex":[0.9985552,0.00007229406,0.0003591852,0.0004039974,0.0003246337,0.0002846823],"domain_scores_gemma":[0.9993179,0.000102201,0.0001101068,0.0001869927,0.0001573469,0.0001254867],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001988105,0.001921583,0.1419008,0.00009395241,0.0004945835,0.0002638641,0.0006789468,0.0005121797,0.8474036,0.00007304388,0.001415218,0.003254059],"study_design_scores_gemma":[0.007526935,0.0005566012,0.3475593,0.0001794236,0.0001546686,0.00002294792,0.00005948167,0.0009638681,0.6386704,0.00003550401,0.004026363,0.0002444691],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922624,0.0002752166,0.000008417417,0.002191087,0.0008691003,0.00113644,0.0000332323,0.00003658882,0.003187468],"genre_scores_gemma":[0.9939904,0.0002402608,0.000103116,0.002571984,0.0001078892,0.0002462082,0.0001214727,0.00002830304,0.002590398],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2087332,"threshold_uncertainty_score":0.9979478,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009770873879898645,"score_gpt":0.2775901308174429,"score_spread":0.2678192569375442,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}