{"id":"W2969495924","doi":"10.21037/jtd.2019.08.03","title":"PEEP titration guided by transpulmonary pressure: lessons from a negative trial","year":2019,"lang":"en","type":"letter","venue":"Journal of Thoracic Disease","topic":"Respiratory Support and Mechanisms","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital","funders":"Instituto de Salud Carlos III","keywords":"ARDS; Medicine; Transpulmonary pressure; Oxygenation; Anesthesia; Mechanical ventilation; Hemodynamics; Acute respiratory distress; Intensive care medicine; Positive end-expiratory pressure; Respiratory physiology; Cardiology; Lung; Internal medicine; Lung volumes","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01961387,0.0008098589,0.00197767,0.0004691884,0.001138829,0.003786142,0.001783035,0.01084348,0.003010873],"category_scores_gemma":[0.07323968,0.0002440736,0.001198645,0.0006817988,0.002619949,0.005174209,0.001063596,0.01317655,0.001556961],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002013686,"about_ca_system_score_gemma":0.001856383,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006327442,"about_ca_topic_score_gemma":0.0009947679,"domain_scores_codex":[0.9937823,0.003412973,0.0009233456,0.0005231927,0.001065178,0.000293052],"domain_scores_gemma":[0.952747,0.03756373,0.001502291,0.001559383,0.003535945,0.003091633],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.01591815,0.00193086,0.004319269,0.003087502,0.001149241,0.008020944,0.0006603454,0.001042149,0.00278267,0.04448355,0.3530076,0.5635977],"study_design_scores_gemma":[0.01911082,0.009008954,0.005783607,0.01308827,0.001659259,0.007025957,0.0008901971,0.002984564,0.001933277,0.1545131,0.7837103,0.0002917412],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.01723344,0.07433947,0.002912503,0.8432738,0.04593481,0.0002264569,0.0002685377,0.0001040681,0.01570701],"genre_scores_gemma":[0.1707166,0.0452788,0.007974473,0.6743939,0.09660389,0.0005946804,0.0002793446,0.0001444776,0.004013896],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.01961387,"threshold_uncertainty_score":0.1037292,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04666954395097021,"score_gpt":0.3634312353744846,"score_spread":0.3167616914235143,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}