{"id":"W2969670076","doi":"10.1101/740498","title":"TPR is required for the nuclear export of mRNAs and lncRNAs from intronless and intron-poor genes","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Intron; Nuclear export signal; RNA splicing; Biology; Gene; Messenger RNA; Cell biology; Nuclear protein; Nuclear gene; Cell nucleus; Nucleus; Molecular biology; Genetics; RNA; Transcription factor; Genome","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001235759,0.0002018432,0.0002412372,0.0001319297,0.0001642399,0.0003213164,0.0001326987,0.0002414707,0.001934482],"category_scores_gemma":[0.0002001577,0.0001331344,0.0002198917,0.00008033553,0.0002257641,0.0001383314,0.0002205708,0.000327979,0.0009391753],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001486402,"about_ca_system_score_gemma":0.0001647997,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003184653,"about_ca_topic_score_gemma":0.000340093,"domain_scores_codex":[0.9998738,0.00001548148,0.00001218566,0.0000386891,0.00003754579,0.00002240973],"domain_scores_gemma":[0.9998214,0.00002805917,0.00005834119,0.00002977703,0.00001515513,0.00004739777],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005172954,0.000004921578,0.0004268139,0.0000172514,0.000002763853,0.0002548705,0.000009341438,0.00002024132,0.9986225,0.00006521241,0.00005497137,0.0004692919],"study_design_scores_gemma":[0.00002360228,0.0001013156,0.02704304,0.000007284099,0.0000142947,0.002853063,0.00004857788,0.001416931,0.964505,0.0001431942,0.003836286,0.000007438825],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920207,0.0008910696,0.004738019,0.0001439664,0.00003558338,0.000009680533,0.0006920124,0.0001994809,0.001269485],"genre_scores_gemma":[0.9927177,0.0002413345,0.002757379,0.00006075123,0.00001584464,0.000009724156,0.001409722,0.00009028423,0.002697121],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001934482,"threshold_uncertainty_score":0.006471455,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01397661378300634,"score_gpt":0.2368955064412162,"score_spread":0.2229188926582099,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}