{"id":"W2969691243","doi":"10.3390/cancers11091240","title":"Role of the Microenvironment in Regulating Normal and Cancer Stem Cell Activity: Implications for Breast Cancer Progression and Therapy Response","year":2019,"lang":"en","type":"review","venue":"Cancers","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; University of Manitoba; Research Institute in Oncology and Hematology; London Health Sciences Centre; CancerCare Manitoba","funders":"","keywords":"Cancer; Breast cancer; Medicine; Cancer stem cell; Tumor microenvironment; Cancer research; Oncology; Internal medicine; Bioinformatics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002123971,0.0002447469,0.0008587858,0.00008054033,0.00006490164,0.00001098845,0.00008771179,0.0001298614,0.00002170526],"category_scores_gemma":[0.000002359315,0.0001575151,0.0001679406,0.0001610973,0.0001383389,0.00004052756,0.00006797389,0.0001900668,1.470366e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001151133,"about_ca_system_score_gemma":0.001405509,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005235218,"about_ca_topic_score_gemma":0.0001193501,"domain_scores_codex":[0.9988847,0.00009501969,0.0002936552,0.0003824993,0.0001130675,0.000231068],"domain_scores_gemma":[0.9990252,0.0001037081,0.0004132921,0.0003526112,0.0000286153,0.00007656617],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005873998,0.00001731089,0.0006875647,0.005803373,0.00007155948,1.149618e-7,0.0001826966,0.000008840256,0.005538288,0.000001143845,0.00005514055,0.9870465],"study_design_scores_gemma":[0.001757537,0.0001210214,0.01568178,0.01335559,0.0007898271,0.00002500708,0.0001041427,0.00001946907,0.002130264,0.000002308937,0.9657578,0.0002551842],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03619538,0.9596536,0.000001413901,0.000383761,0.0001030754,0.002571466,0.001057063,0.000004976417,0.00002927567],"genre_scores_gemma":[0.01051737,0.9875352,0.0000487101,0.0000552454,0.00008172145,0.001241695,0.000005683889,0.00004693604,0.0004674206],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9867914,"threshold_uncertainty_score":0.6423278,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04121783527169594,"score_gpt":0.3483532211997019,"score_spread":0.307135385928006,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}