{"id":"W2969691243","doi":"10.3390/cancers11091240","title":"Role of the Microenvironment in Regulating Normal and Cancer Stem Cell Activity: Implications for Breast Cancer Progression and Therapy Response","year":2019,"lang":"en","type":"review","venue":"Cancers","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; University of Manitoba; Research Institute in Oncology and Hematology; London Health Sciences Centre; CancerCare Manitoba","funders":"","keywords":"Cancer; Breast cancer; Medicine; Cancer stem cell; Tumor microenvironment; Cancer research; Oncology; Internal medicine; Bioinformatics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005320946,0.000661613,0.001137094,0.001814932,0.0002739582,0.001015393,0.0007672643,0.001256797,0.002494166],"category_scores_gemma":[0.0007466467,0.0001898855,0.000353203,0.001727621,0.0006921362,0.001252886,0.0006863193,0.001662931,0.001414618],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008120277,"about_ca_system_score_gemma":0.001035748,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009164643,"about_ca_topic_score_gemma":0.001699521,"domain_scores_codex":[0.9998133,0.00003692249,0.00002421697,0.00003090221,0.00007297,0.00002178599],"domain_scores_gemma":[0.9996351,0.0001842359,0.00004210629,0.000009607194,0.00009361016,0.00003536732],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005974204,0.00005491133,0.0002238322,0.01185403,0.00006063708,0.0001845347,0.00006506743,0.0003842991,0.002162289,0.00607337,0.02359908,0.9552782],"study_design_scores_gemma":[0.000009600749,0.00008519825,0.0009275056,0.003214041,0.00006726002,0.001224742,0.00007862705,0.00009991262,0.000509428,0.00310786,0.9906574,0.00001832719],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006354119,0.9988869,0.00007220832,0.0002849023,0.0001350252,0.000001554455,0.000007823079,0.000004286702,0.0005437199],"genre_scores_gemma":[0.0004614938,0.9989185,0.00008050837,0.0001539763,0.000121686,0.000003192212,0.00001008932,7.679832e-7,0.0002497552],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002494166,"threshold_uncertainty_score":0.008343756,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04121783527169594,"score_gpt":0.3483532211997019,"score_spread":0.307135385928006,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}