{"id":"W2969722359","doi":"10.3233/blc-190228","title":"Investigating the STING Pathway to Explain Mechanisms of BCG Failures in Non-Muscle Invasive Bladder Cancer: Prognostic and Therapeutic Implications","year":2019,"lang":"en","type":"article","venue":"Bladder Cancer","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University; Kingston Health Sciences Centre; Queen's University","funders":"","keywords":"Sting; Bladder cancer; Medicine; Cancer; Oncology; Cancer research; Internal medicine; Engineering","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003133407,0.0002515904,0.0003481669,0.0001226702,0.000175305,0.00002457505,0.0003788356,0.000185728,0.0006486006],"category_scores_gemma":[0.0001197043,0.0001960998,0.00005731038,0.0003815124,0.0002232837,0.000086699,0.0002110337,0.0003770767,0.00005801702],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001138701,"about_ca_system_score_gemma":0.0004002448,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002508453,"about_ca_topic_score_gemma":0.002781205,"domain_scores_codex":[0.9983747,0.0001723397,0.0004316335,0.0004640167,0.00007068083,0.0004866247],"domain_scores_gemma":[0.9985543,0.0005838689,0.0002410568,0.0004617783,0.0001263372,0.00003269498],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001827561,0.00003928924,0.0263855,0.00008128097,0.0002036636,5.082578e-7,0.005736802,0.0005527579,0.9455311,0.001656072,0.0004923136,0.0193024],"study_design_scores_gemma":[0.002337849,0.0003211769,0.2882311,0.001012461,0.0001676514,0.00001619645,0.007183345,0.00009131838,0.6874661,0.004524332,0.007874943,0.0007735404],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.984094,0.009743084,0.0002207314,0.003014623,0.0006871913,0.001572646,0.00008341476,0.00003863513,0.0005456971],"genre_scores_gemma":[0.9959351,0.0002456451,0.0002486496,0.001762373,0.00003934302,0.001115514,0.0000125466,0.00004354563,0.0005973221],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2618456,"threshold_uncertainty_score":0.799672,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01753233826615099,"score_gpt":0.2573248348540697,"score_spread":0.2397924965879187,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}