{"id":"W2969809290","doi":"10.1038/s41598-019-48548-9","title":"Disease-specific and glucocorticoid-responsive serum biomarkers for Duchenne Muscular Dystrophy","year":2019,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"Congressionally Directed Medical Research Programs; Children's Hospital of Pittsburgh; U.S. Department of Veterans Affairs; University of Alberta; Hebrew University of Jerusalem; Muscular Dystrophy Association; Children's National Hospital; Texas Children's Hospital; University of Pittsburgh; National Science Foundation; National Institutes of Health; U.S. Department of Health and Human Services; University of Minnesota; Eunice Kennedy Shriver National Institute of Child Health and Human Development; U.S. Department of Defense","keywords":"Duchenne muscular dystrophy; Disease; Glucocorticoid; Muscular dystrophy; Medicine; Neuromuscular disease; Bioinformatics; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005980127,0.0004731933,0.0004327414,0.001297341,0.0002500883,0.0004801022,0.0001988579,0.0003902641,0.0009117529],"category_scores_gemma":[0.001031977,0.0001516425,0.0002771713,0.0006277762,0.0002482779,0.0002110609,0.000291755,0.0004758781,0.0002047178],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002441397,"about_ca_system_score_gemma":0.0002155212,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006713961,"about_ca_topic_score_gemma":0.001281973,"domain_scores_codex":[0.9996319,0.0001024055,0.0000670269,0.00007131065,0.00009824103,0.0000292255],"domain_scores_gemma":[0.9994649,0.0001594571,0.00019715,0.00003331894,0.00007095814,0.00007407796],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001191962,0.0001505255,0.8356621,0.000187581,0.0002065388,0.000935827,0.0001635543,0.0003331123,0.1345109,0.00008551202,0.000542886,0.02602931],"study_design_scores_gemma":[0.00001995187,0.0003952228,0.9800371,0.00002632451,0.0001240647,0.001750789,0.0001234684,0.0007322138,0.01577211,0.00007553893,0.000930604,0.00001257669],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937838,0.004032904,0.001082193,0.0001037722,0.00002463534,0.00001817792,0.0002842215,0.00004773722,0.0006225452],"genre_scores_gemma":[0.9963288,0.0008690211,0.001939879,0.00008115566,0.00002056746,0.00001652946,0.0003225236,0.000005903094,0.0004157228],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001297341,"threshold_uncertainty_score":0.003162622,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00704935776437431,"score_gpt":0.2217116272001793,"score_spread":0.214662269435805,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}