{"id":"W2969846817","doi":"10.1111/liv.14223","title":"Biology and significance of alpha‐fetoprotein in hepatocellular carcinoma","year":2019,"lang":"en","type":"review","venue":"Liver International","topic":"Hepatocellular Carcinoma Treatment and Prognosis","field":"Medicine","cited_by":592,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital","funders":"Cancer Research UK; Eli Lilly and Company","keywords":"Hepatocellular carcinoma; Biomarker; Clinical significance; Alpha-fetoprotein; Medicine; Disease; Cancer; Stage (stratigraphy); Angiogenesis; Oncology; Biomarker discovery; Internal medicine; Bioinformatics; Cancer research; Biology; Proteomics; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003988126,0.0006519712,0.00114161,0.00211283,0.0002174045,0.0008135022,0.0005009677,0.0007663501,0.001628986],"category_scores_gemma":[0.0005817991,0.0001973562,0.0004011299,0.002333468,0.0004654011,0.0010243,0.0005451964,0.001264126,0.0009847338],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006859495,"about_ca_system_score_gemma":0.001044221,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001345734,"about_ca_topic_score_gemma":0.001765501,"domain_scores_codex":[0.999846,0.00003039335,0.00002899938,0.00002205046,0.00005939469,0.00001319855],"domain_scores_gemma":[0.9997991,0.00009371234,0.00003259495,0.00000549218,0.00005432951,0.00001481362],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006206051,0.00004030148,0.000358416,0.02672946,0.0001200758,0.0003768868,0.0001116422,0.0004302594,0.002066741,0.004947325,0.02988271,0.9348741],"study_design_scores_gemma":[0.00001083429,0.00007132594,0.001639697,0.006261229,0.0001266089,0.002851529,0.0000900571,0.00008816016,0.0004816506,0.00279706,0.9855606,0.00002129668],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005167695,0.9992868,0.00003648122,0.0001544638,0.0001047036,0.000001154499,0.000005569486,0.000001844116,0.0003573423],"genre_scores_gemma":[0.0003719735,0.9992626,0.00003626327,0.00006798779,0.0000823018,0.000001486399,0.000009132182,3.952632e-7,0.000167864],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00211283,"threshold_uncertainty_score":0.005449533,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1258064352287268,"score_gpt":0.3291225500715129,"score_spread":0.2033161148427861,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}