{"id":"W2969887139","doi":"10.3389/fneur.2019.00968","title":"Expression of Human Endogenous Retrovirus-K in Spinal and Bulbar Muscular Atrophy","year":2019,"lang":"en","type":"article","venue":"Frontiers in Neurology","topic":"Neurogenetic and Muscular Disorders Research","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; University of Manitoba; University of Winnipeg","funders":"Natural Sciences and Engineering Research Council of Canada; Universities Space Research Association; University of Winnipeg; BC Children's Hospital; Children's Hospital Foundation; Rare Disease Foundation","keywords":"Spinal and bulbar muscular atrophy; Amyotrophic lateral sclerosis; Polyglutamine tract; Androgen receptor; Biology; Neurodegeneration; Atrophy; Motor neuron; Pathology; Immunology; Medicine; Spinal cord; Disease; Neuroscience; Genetics; Huntington's disease; Prostate cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002896945,0.0001890176,0.000134706,0.0002516074,0.0001499738,0.0003304179,0.0001915438,0.0003639566,0.001153873],"category_scores_gemma":[0.0002708807,0.00008284285,0.0001896977,0.0001842033,0.0002904861,0.0001565354,0.0001746446,0.0003883533,0.0004513459],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003764363,"about_ca_system_score_gemma":0.000162333,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003893401,"about_ca_topic_score_gemma":0.0005434692,"domain_scores_codex":[0.9998004,0.00004876067,0.00002451226,0.00004050633,0.00005442614,0.00003137821],"domain_scores_gemma":[0.999891,0.00003705574,0.00002285727,0.00001908383,0.00001386387,0.00001608449],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003071953,0.00007756328,0.002168253,0.0001033167,0.00001567196,0.0002779991,0.00004586195,0.00009866742,0.9936698,0.0001790918,0.0001101141,0.002946629],"study_design_scores_gemma":[0.0001448422,0.003541925,0.05549007,0.0001076121,0.0001328371,0.007541833,0.0002571338,0.004031151,0.9144796,0.0004398787,0.01381489,0.00001817273],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992376,0.003526701,0.002375429,0.00009890255,0.00006267987,0.00004183566,0.0003989728,0.00005749393,0.001061976],"genre_scores_gemma":[0.9939567,0.001363149,0.002582108,0.00006457999,0.00002091939,0.00003070659,0.0009477632,0.00001393021,0.001020116],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001153873,"threshold_uncertainty_score":0.003860116,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01558316469859992,"score_gpt":0.266026225207146,"score_spread":0.2504430605085461,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}