{"id":"W2969952375","doi":"10.1016/j.imbio.2019.08.007","title":"RAGE and CCR7 mediate the transmigration of Zika-infected monocytes through the blood-brain barrier","year":2019,"lang":"en","type":"article","venue":"Immunobiology","topic":"Mosquito-borne diseases and control","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"HMGB1; Rage (emotion); CCL19; Chemokine receptor; Blood–brain barrier; Chemokine; Immunology; Receptor; Monocyte; C-C chemokine receptor type 7; Biology; CX3CR1; Chemokine receptor CCR5; Inflammation; Cell biology; Medicine; Neuroscience; Central nervous system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001993332,0.0001215133,0.0002840664,0.00002034411,0.00006633511,0.000009238394,0.0001225031,0.00009688267,0.0003327834],"category_scores_gemma":[0.00008585443,0.00005861588,0.0001086504,0.00008602622,0.0002033326,0.0000432913,0.00002728693,0.0001474132,0.00001936895],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005753571,"about_ca_system_score_gemma":0.00005471798,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002379669,"about_ca_topic_score_gemma":0.00003556356,"domain_scores_codex":[0.9991649,0.0001708275,0.0002363328,0.0001750805,0.00006796139,0.0001849193],"domain_scores_gemma":[0.9990017,0.0004258944,0.00009209109,0.0003948974,0.000058382,0.00002697058],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001441795,0.000233966,0.03825616,0.0001292815,0.001081889,0.00001110808,0.005896451,0.00001740518,0.9263324,0.01064068,0.0012233,0.01473557],"study_design_scores_gemma":[0.02347896,0.00422414,0.7673415,0.0002041577,0.002555027,0.0002672316,0.004324585,0.0020321,0.063501,0.004252247,0.1271628,0.0006563014],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9843114,0.008820143,0.00006822029,0.005280663,0.0001706351,0.0006430069,0.00002777549,0.00002242388,0.0006557152],"genre_scores_gemma":[0.9969281,0.0004850154,0.00001365614,0.001810483,0.00007818631,0.00004156879,0.00004597603,0.00001148251,0.0005855295],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8628314,"threshold_uncertainty_score":0.3643745,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004981885932952449,"score_gpt":0.2367449371288031,"score_spread":0.2317630511958506,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}