{"id":"W2969992885","doi":"10.3324/haematol.2019.224204","title":"Chimeric antigen receptor T-cell therapy for multiple myeloma: a consensus statement from The European Myeloma Network","year":2019,"lang":"en","type":"article","venue":"Haematologica","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotel Dieu Hospital","funders":"","keywords":"Chimeric antigen receptor; Multiple myeloma; Medicine; Cell therapy; Clinical trial; Antigen; Daratumumab; Monoclonal antibody; Immunology; Targeted therapy; Bortezomib; Cancer research; Immunotherapy; Oncology; Cancer; Internal medicine; Antibody; Cell; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01577992,0.0008089403,0.0016393,0.001338153,0.0009113946,0.0024597,0.003338909,0.008588647,0.001505696],"category_scores_gemma":[0.006275469,0.0004007247,0.001510019,0.001772979,0.001652161,0.00185918,0.001976351,0.009386226,0.00225444],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002564557,"about_ca_system_score_gemma":0.01270741,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004223195,"about_ca_topic_score_gemma":0.005581839,"domain_scores_codex":[0.9948331,0.001223482,0.001013511,0.0003532934,0.002126103,0.0004504282],"domain_scores_gemma":[0.9925427,0.001725065,0.00107177,0.0001915361,0.003339446,0.001129454],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003125766,0.0002765604,0.0009674721,0.004164373,0.0001273452,0.0005988369,0.0001743486,0.0009567302,0.005102194,0.01134533,0.6002674,0.3757069],"study_design_scores_gemma":[0.0001010522,0.0001297641,0.00131295,0.002491092,0.00009508691,0.0005685005,0.00008404694,0.0002260248,0.00128651,0.002864228,0.990813,0.00002766058],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"review","genre_gemma":"methods","genre_scores_codex":[0.002038179,0.4795946,0.008488391,0.4610085,0.03171284,0.0005402317,0.0009527625,0.0001995937,0.01546496],"genre_scores_gemma":[0.02305911,0.6044033,0.03544489,0.2757413,0.0238413,0.001447129,0.00380083,0.0002155079,0.03204675],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.01577992,"threshold_uncertainty_score":0.08345318,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04202163171986532,"score_gpt":0.2957468530958976,"score_spread":0.2537252213760323,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}