{"id":"W2969996564","doi":"10.1111/mmi.14374","title":"Heme acquisition by Shu1 requires Nbr1 and proteins of the ESCRT complex in <i>Schizosaccharomyces pombe</i>","year":2019,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Hemin; ESCRT; Biology; Schizosaccharomyces pombe; Vacuole; Heme; Cell biology; Endosome; Schizosaccharomyces; Ubiquitin; Immunoprecipitation; Vacuolar protein sorting; Internalization; Biochemistry; Cell; Saccharomyces cerevisiae; Gene; Intracellular; Enzyme; Cytoplasm","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005800304,0.0003162086,0.0001682178,0.0001037204,0.0002547401,0.0003389699,0.0001621934,0.0001509004,0.0007665579],"category_scores_gemma":[0.00009896654,0.0001571029,0.0002145317,0.0001002926,0.0001350479,0.0001808285,0.0002158236,0.0003047647,0.0005163215],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005574854,"about_ca_system_score_gemma":0.0001920373,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002853777,"about_ca_topic_score_gemma":0.003752416,"domain_scores_codex":[0.9999555,0.000005984834,0.000005173627,0.00001010435,0.00001204585,0.00001122648],"domain_scores_gemma":[0.9999273,0.000008986701,0.00001895285,0.00001274506,0.000008844154,0.00002315208],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005542389,0.00000689331,0.0004545684,0.00001645241,0.000003190027,0.00007390476,0.00001436115,0.00008654427,0.9986859,0.00009546727,0.00003327716,0.000474018],"study_design_scores_gemma":[0.000009060675,0.00007095104,0.01402305,0.000007563615,0.00001271286,0.0003314262,0.00008749311,0.002123189,0.9807272,0.00009099925,0.002508457,0.000007770625],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969701,0.0003033466,0.001390328,0.00004682491,0.000007227007,0.000005913414,0.0003828402,0.00005886617,0.0008346069],"genre_scores_gemma":[0.9951245,0.0001553021,0.001235076,0.0000220916,0.000001643989,0.000006633924,0.001368197,0.00003891541,0.002047698],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002853777,"threshold_uncertainty_score":0.005674303,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003680457494879276,"score_gpt":0.1879479870402773,"score_spread":0.184267529545398,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}