{"id":"W2969996564","doi":"10.1111/mmi.14374","title":"Heme acquisition by Shu1 requires Nbr1 and proteins of the ESCRT complex in <i>Schizosaccharomyces pombe</i>","year":2019,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Hemin; ESCRT; Biology; Schizosaccharomyces pombe; Vacuole; Heme; Cell biology; Endosome; Schizosaccharomyces; Ubiquitin; Immunoprecipitation; Vacuolar protein sorting; Internalization; Biochemistry; Cell; Saccharomyces cerevisiae; Gene; Intracellular; Enzyme; Cytoplasm","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001272499,0.0001494765,0.0001965819,0.00003430982,0.00002956167,0.000007020963,0.0001843939,0.0002054762,0.00004974746],"category_scores_gemma":[0.000007139203,0.0001223626,0.00008769563,0.00008311554,0.0001534682,0.000003720342,0.00009307339,0.00009385798,0.000004955918],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000865793,"about_ca_system_score_gemma":0.00002547118,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005642338,"about_ca_topic_score_gemma":0.00004308962,"domain_scores_codex":[0.9990636,0.0001052982,0.0002419349,0.0003372974,0.00004438055,0.0002074781],"domain_scores_gemma":[0.9995264,0.000004923559,0.00009819014,0.0003101642,0.00003329048,0.00002699731],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008619973,0.00004514165,0.01215576,0.0000339499,0.00002349874,0.000001931814,0.00003261261,0.000007139518,0.9873003,0.0001355071,0.0001027591,0.00007515656],"study_design_scores_gemma":[0.0008208217,0.0001956945,0.004112587,0.00002478557,0.00001175938,0.00003082716,0.00002401597,0.00001088426,0.9742327,0.00007202406,0.02030757,0.0001563691],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965378,0.001513028,0.0008658657,0.0002443283,0.00007489842,0.000454994,0.00006846636,0.000005658285,0.0002349674],"genre_scores_gemma":[0.9972486,0.00007392135,0.0001815643,0.0004386439,0.00001606631,0.00001317814,0.001887419,0.0000166097,0.0001239645],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02020481,"threshold_uncertainty_score":0.4989801,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003680457494879276,"score_gpt":0.1879479870402773,"score_spread":0.184267529545398,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}