{"id":"W2970034116","doi":"10.1073/pnas.1907833116","title":"A promising bioconjugate vaccine against hypervirulent <i>Klebsiella pneumoniae</i>","year":2019,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":196,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Small Business Technology Transfer; Children's Discovery Institute","keywords":"Klebsiella pneumoniae; Bioconjugation; Pathogen; Microbiology; Immunity; Virology; Biology; Immunology; Immune system; Escherichia coli; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006336675,0.00009532976,0.0001300489,0.00004929752,0.00007814567,0.00002085315,0.0006376555,0.00008964298,0.000007551329],"category_scores_gemma":[0.0001530978,0.00006483376,0.00007457005,0.0002479806,0.0002284154,0.00002046313,0.0001861048,0.0000749805,0.000003851346],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001173975,"about_ca_system_score_gemma":0.00003378826,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001150429,"about_ca_topic_score_gemma":3.892744e-8,"domain_scores_codex":[0.9988257,0.00000537556,0.0002678794,0.000277368,0.0004764302,0.0001472213],"domain_scores_gemma":[0.9994352,0.00001526774,0.0003351115,0.00001481871,0.0001742066,0.00002540629],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002170319,0.00002149174,0.04335222,0.00005114692,0.00001226735,2.186359e-9,0.00001579834,0.00002806583,0.9549025,0.001114767,0.0003489137,0.000131176],"study_design_scores_gemma":[0.0002035162,0.00006695216,0.05059804,0.00009460661,0.000005693272,0.000005167401,0.00006167682,0.0001378648,0.94603,0.001234472,0.00147074,0.00009131338],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910899,0.0001512414,4.79434e-7,0.001022466,0.0000314405,0.0002144542,0.000008994619,0.000004024464,0.007477032],"genre_scores_gemma":[0.9982976,0.00009805353,0.0007314187,0.0003683657,0.00007587573,0.000002240552,4.156835e-7,0.000005809877,0.00042025],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008872487,"threshold_uncertainty_score":0.2643844,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01674144254360705,"score_gpt":0.2695568396978987,"score_spread":0.2528153971542917,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}