{"id":"W2970040822","doi":"10.1016/j.bbmt.2019.08.012","title":"Comparison of High Doses of Total Body Irradiation in Myeloablative Conditioning before Hematopoietic Cell Transplantation","year":2019,"lang":"en","type":"article","venue":"Biology of Blood and Marrow Transplantation","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"National Institute of Allergy and Infectious Diseases; Office of Naval Research; Pharmacyclics; Kite Pharma; Health Resources and Services Administration; National Institutes of Health; CytoSen Therapeutics; Swedish Orphan Biovitrum; Janssen Scientific Affairs; Mundipharma EDO; Astellas Pharma; Adaptive Biotechnologies; Pfizer; Incyte; bluebird bio; Medical College of Wisconsin; Chimerix; Medac; Jazz Pharmaceuticals; Takeda Oncology; University of Minnesota; Karyopharm Therapeutics; Sanofi Genzyme; Patient-Centered Outcomes Research Institute; HistoGenetics; U.S. Navy; Celgene; U.S. Department of Defense; Sanofi; Spectrum Pharmaceuticals; Amgen; Government of South Australia; National Heart, Lung, and Blood Institute; Novartis Pharmaceuticals Corporation; Bristol-Myers Squibb; Astellas Pharma US; Atara Biotherapeutics; National Cancer Institute; Gilead Sciences","keywords":"Medicine; Total body irradiation; Conditioning; Hematopoietic cell; Transplantation; Hematopoietic stem cell transplantation; Haematopoiesis; Internal medicine; Stem cell; Cyclophosphamide; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002400496,0.000220476,0.0005510235,0.000378023,0.0001708042,0.0005987529,0.000365997,0.0003654015,0.0008927734],"category_scores_gemma":[0.002983696,0.0001322326,0.0009050412,0.0004470908,0.0003353626,0.0003688499,0.0004112016,0.0008759638,0.0001090778],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007819679,"about_ca_system_score_gemma":0.0005938663,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000649389,"about_ca_topic_score_gemma":0.001190303,"domain_scores_codex":[0.9986676,0.0006956411,0.0001306673,0.0001203277,0.0002448597,0.0001408239],"domain_scores_gemma":[0.9977864,0.001047152,0.0005415604,0.0001218976,0.0001053918,0.0003975225],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.4951445,0.009968432,0.2840579,0.0007332622,0.003446088,0.0001829619,0.0005158389,0.01458118,0.01614538,0.0009820287,0.001035834,0.1732066],"study_design_scores_gemma":[0.009245045,0.3043158,0.6729273,0.0002324538,0.001886498,0.0002235995,0.0002634334,0.003000446,0.005394994,0.0004631937,0.002011369,0.00003597563],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977188,0.001374176,0.0001684147,0.00003704389,0.00002861157,0.00003753621,0.00004029222,0.000004196944,0.000590848],"genre_scores_gemma":[0.9991387,0.0003954468,0.0001189395,0.00004441191,0.00004060967,0.00003802087,0.0001422524,0.000002279784,0.00007927411],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002400496,"threshold_uncertainty_score":0.01269519,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009513624649296965,"score_gpt":0.2673343625609437,"score_spread":0.2578207379116467,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}