{"id":"W2970066205","doi":"10.1016/j.clml.2019.07.245","title":"Assessing the Clinical Significance of Major (MMR) and Deep (DMR) Molecular Responses for Overall (OS), Progression-Free (PFS) and Event-Free (EFS) Survival in Patients with Chronic Myeloid Leukemia (CML) Treated with Tyrosine Kinase Inhibitors (TKIs)","year":2019,"lang":"en","type":"article","venue":"Clinical Lymphoma Myeloma & Leukemia","topic":"Chronic Myeloid Leukemia Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Precision Nanosystems (Canada)","funders":"","keywords":"Myeloid leukemia; Overall survival; Medicine; Internal medicine; Oncology; Clinical significance; Event (particle physics); Progression-free survival","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001733348,0.0003126814,0.0005434658,0.0003655703,0.0002093089,0.0006579696,0.0003239173,0.0004570403,0.001488101],"category_scores_gemma":[0.002186592,0.0001167778,0.0006209198,0.0003665785,0.0003123504,0.0007311305,0.0005379395,0.0007152178,0.0002271711],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004581517,"about_ca_system_score_gemma":0.0003342445,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004214265,"about_ca_topic_score_gemma":0.001099767,"domain_scores_codex":[0.9994366,0.0002514541,0.00005852064,0.00008636443,0.0000690297,0.00009808358],"domain_scores_gemma":[0.9983414,0.0007299894,0.0004615596,0.00005564358,0.00009440591,0.0003170613],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01977523,0.0004382213,0.9110626,0.0001531071,0.0004288075,0.00008493559,0.0001242103,0.001264701,0.004150005,0.0001871303,0.0005162278,0.0618148],"study_design_scores_gemma":[0.0004508481,0.01060471,0.9807743,0.00003549396,0.0005262219,0.0004368811,0.0002314195,0.003068185,0.001515005,0.0004823145,0.001855061,0.00001958972],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957194,0.001821918,0.0002889353,0.0002386102,0.00001742871,0.00004455315,0.0003155722,0.00001124479,0.001542335],"genre_scores_gemma":[0.9988938,0.0001932718,0.0002031303,0.00009493345,0.00003262028,0.00002439818,0.0002822647,0.000001965872,0.0002736346],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001733348,"threshold_uncertainty_score":0.009166956,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01722743346317267,"score_gpt":0.3205819347229885,"score_spread":0.3033545012598158,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}