{"id":"W2970189291","doi":"10.1111/cmi.13107","title":"Here, there, and everywhere: How pathogenic<i>Escherichia coli</i>sense and respond to gastrointestinal biogeography","year":2019,"lang":"en","type":"review","venue":"Cellular Microbiology","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; Michael Smith Health Research BC; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Citrobacter rodentium; Biology; Colonisation; Microbiology; Enteropathogenic Escherichia coli; Effector; Secretion; Pathogen; Host (biology); Gastrointestinal tract; Type three secretion system; Citrobacter; Escherichia coli; Intestinal epithelium; Enterobacteriaceae; Virulence; Colonization; Epithelium; Immunology; Ecology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003055732,0.0005556364,0.0008730423,0.001121432,0.0002506313,0.001270852,0.0005884756,0.001144953,0.00302401],"category_scores_gemma":[0.0005028177,0.0001941798,0.0002792442,0.001360764,0.0004913567,0.001918328,0.0005852841,0.001239956,0.00253972],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005573909,"about_ca_system_score_gemma":0.00108669,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009854452,"about_ca_topic_score_gemma":0.001627843,"domain_scores_codex":[0.9998947,0.00002103374,0.00001383711,0.00002165846,0.00003313789,0.00001564183],"domain_scores_gemma":[0.9998215,0.00007423142,0.00002334677,0.000007284868,0.00005006661,0.00002360104],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006917425,0.00003267046,0.0001931238,0.01730507,0.00005952903,0.0001492042,0.0001496712,0.0002961869,0.004281159,0.007875578,0.03582819,0.9337603],"study_design_scores_gemma":[0.000003870897,0.00004420798,0.0004644981,0.00213128,0.00003223083,0.0003726914,0.00008779197,0.00003441346,0.0004079586,0.001714319,0.994696,0.00001082631],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002080832,0.995974,0.0002020117,0.0008543864,0.0005388573,0.000004313237,0.00002452999,0.00001144962,0.002182306],"genre_scores_gemma":[0.000829776,0.9973142,0.0001810724,0.000361976,0.0001927923,0.000004358411,0.00002630188,0.000002187642,0.001087359],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00302401,"threshold_uncertainty_score":0.01011634,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02346868042488579,"score_gpt":0.2723382583671642,"score_spread":0.2488695779422784,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}