{"id":"W2970241796","doi":"10.1002/art.41089","title":"Comprehensive Profiling of the Rheumatoid Arthritis Antibody Repertoire","year":2019,"lang":"en","type":"article","venue":"Arthritis & Rheumatology","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University of Toronto; Mount Sinai Hospital","funders":"","keywords":"Epitope; Biomarker; Autoantibody; Human proteome project; Cohort; Medicine; Antibody; Rheumatoid arthritis; Peptide; Proteome; Immunology; Internal medicine; Biology; Bioinformatics; Proteomics; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004891793,0.0003717932,0.0002987091,0.0009221837,0.000177278,0.0003583464,0.0001699247,0.000281272,0.0005364617],"category_scores_gemma":[0.0006502285,0.0001276653,0.000188986,0.0004804749,0.0001372568,0.0001745851,0.0003448992,0.0002448338,0.0002330292],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001138014,"about_ca_system_score_gemma":0.0001016017,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002467492,"about_ca_topic_score_gemma":0.0003140937,"domain_scores_codex":[0.9994835,0.0001075184,0.00003789199,0.0001612385,0.0001466263,0.0000631642],"domain_scores_gemma":[0.9996209,0.0001018372,0.0000895738,0.00003845602,0.00009467775,0.00005446538],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004827301,0.00007889324,0.1853065,0.0001383339,0.0001570562,0.0002681469,0.0001082514,0.0007300646,0.7856709,0.00004672527,0.000236225,0.0267761],"study_design_scores_gemma":[0.00004131239,0.001572882,0.8778641,0.00003505876,0.000227299,0.004692624,0.0001144852,0.003133168,0.1088139,0.0001956689,0.003284746,0.00002481353],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955212,0.001090932,0.002445024,0.00003021874,0.000003694973,0.00001809738,0.0005044461,0.00004148655,0.0003449819],"genre_scores_gemma":[0.9937522,0.0003343579,0.004427729,0.00006451672,0.00001516105,0.00002947004,0.001129022,0.000006984364,0.0002405932],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009221837,"threshold_uncertainty_score":0.00258702,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01029270310208317,"score_gpt":0.2693536379023682,"score_spread":0.259060934800285,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}