{"id":"W2970261394","doi":"10.1097/txd.0000000000000842","title":"Pediatric Outcomes in Transplant: PersOnaliSing Immunosuppression To ImproVe Efficacy (POSITIVE Study): The Collaboration and Design of a National Transplant Precision Medicine Program","year":2018,"lang":"en","type":"article","venue":"Transplantation Direct","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; Montreal Children's Hospital; Centre Hospitalier Universitaire Sainte-Justine; Alberta Children's Hospital; Health Sciences Centre; University of Toronto; SickKids Foundation; Hospital for Sick Children; University of British Columbia; University of Alberta; Canadian Natural Resources","funders":"Canadian Institutes of Health Research; Hospital for Sick Children; Astellas Pharma","keywords":"Immunosuppression; Medicine; Hematopoietic stem cell transplantation; Young adult; Internal medicine; Transplantation; Organ transplantation; Pediatrics; Intensive care medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02199407,0.0003794806,0.000386992,0.0005731362,0.001813408,0.001135385,0.001179736,0.0006408237,0.001664682],"category_scores_gemma":[0.01243358,0.000392965,0.0005628635,0.000801096,0.001007271,0.0008043487,0.002833269,0.0009895364,0.0002120212],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004621294,"about_ca_system_score_gemma":0.02991553,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.03036468,"about_ca_topic_score_gemma":0.05055134,"domain_scores_codex":[0.9876886,0.00878333,0.0005089552,0.0008618108,0.001195564,0.0009617243],"domain_scores_gemma":[0.9856476,0.003548872,0.00425481,0.001376048,0.001736292,0.003436393],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00387459,0.005102883,0.9102468,0.0002034091,0.0001953425,0.0001729006,0.001822423,0.0006135005,0.000649292,0.001091751,0.005423544,0.07060361],"study_design_scores_gemma":[0.007923882,0.0130869,0.958623,0.0003464292,0.0003614573,0.0002692196,0.002794811,0.001826596,0.001397911,0.0006269373,0.01270423,0.0000384884],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9817311,0.0005156216,0.002491937,0.002070702,0.00006519027,0.008189487,0.001679188,0.00003697846,0.003219917],"genre_scores_gemma":[0.9614353,0.0006874777,0.01949154,0.001607745,0.0001674671,0.01420058,0.001341863,0.00001639084,0.001051659],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03036468,"threshold_uncertainty_score":0.1163172,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02967441413808936,"score_gpt":0.3516972947669728,"score_spread":0.3220228806288834,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}