{"id":"W2970273168","doi":"10.1016/j.ddmod.2019.08.007","title":"Gut microbes as a therapeutic armory","year":2018,"lang":"en","type":"article","venue":"Drug Discovery Today Disease Models","topic":"Clostridium difficile and Clostridium perfringens research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canadian Institute for Advanced Research","funders":"Technion-Israel Institute of Technology; Ministry of Science and Technology, Israel; German-Israeli Foundation for Scientific Research and Development; Glycemic Index Foundation; Canadian Institute for Advanced Research; Henry and Marilyn Taub Foundation; Seerave Foundation; Johnson and Johnson; Israel Science Foundation; Israel Cancer Research Fund","keywords":"Fecal bacteriotherapy; Biology; Microbiome; Gut flora; Disease; Colonisation resistance; Clostridium difficile; Colonization; Host (biology); Dysbiosis; Gut bacteria; Host factors; Gut microbiome; Intensive care medicine; Microbiology; Medicine; Bioinformatics; Immunology; Ecology; Antibiotics; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001299628,0.000721874,0.0008171912,0.001069571,0.0004947431,0.002626685,0.0006181652,0.00196163,0.01093759],"category_scores_gemma":[0.0007741303,0.0001848654,0.0004007788,0.0004786359,0.001632095,0.002863345,0.001656296,0.003007039,0.001758796],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007127672,"about_ca_system_score_gemma":0.0008089468,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002275759,"about_ca_topic_score_gemma":0.0005631963,"domain_scores_codex":[0.9994776,0.0002202314,0.00003068634,0.0000497689,0.0001266879,0.0000951229],"domain_scores_gemma":[0.9994348,0.0001793305,0.00008776833,0.00005641277,0.0000886179,0.0001529993],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002117767,0.0008030098,0.001670135,0.002873715,0.0001422456,0.0009348103,0.0002354892,0.000768871,0.07153184,0.1815976,0.08616809,0.6511565],"study_design_scores_gemma":[0.0004019504,0.003082731,0.001830996,0.001461402,0.0001812488,0.001554747,0.0005589632,0.0008693282,0.01380978,0.06803905,0.9081574,0.00005247046],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02887307,0.77023,0.005382199,0.1232192,0.01239835,0.00007863619,0.0003976969,0.0003018026,0.05911904],"genre_scores_gemma":[0.2669529,0.6269504,0.009578842,0.03470948,0.01792431,0.0001851148,0.0003195682,0.00007824542,0.04330117],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01093759,"threshold_uncertainty_score":0.03658992,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02772328109549444,"score_gpt":0.3006078005725784,"score_spread":0.272884519477084,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}