{"id":"W2970318644","doi":"10.2196/15029","title":"Testing a Real-Time Tenofovir Urine Adherence Assay for Monitoring and Providing Feedback to Preexposure Prophylaxis in Kenya (PUMA): Protocol for a Pilot Randomized Controlled Trial","year":2019,"lang":"en","type":"article","venue":"JMIR Research Protocols","topic":"HIV/AIDS Research and Interventions","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institutes of Health; National Institute of Allergy and Infectious Diseases; Alere","keywords":"Pre-exposure prophylaxis; Medicine; Randomized controlled trial; Emtricitabine; Protocol (science); Focus group; Family medicine; Human immunodeficiency virus (HIV); Men who have sex with men; Viral load; Alternative medicine; Antiretroviral therapy; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.06134013,0.007219911,0.01031247,0.003600586,0.004622297,0.004752217,0.004421557,0.008956098,0.06560393],"category_scores_gemma":[0.05428792,0.004271555,0.005609289,0.004449032,0.004720553,0.003980137,0.002835648,0.009223364,0.01206524],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.006786935,"about_ca_system_score_gemma":0.02247929,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002883886,"about_ca_topic_score_gemma":0.005307974,"domain_scores_codex":[0.9562168,0.02861319,0.004548806,0.002604203,0.004307126,0.003709962],"domain_scores_gemma":[0.9708378,0.007402724,0.006139796,0.003602553,0.008057843,0.003959329],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8051857,0.03879122,0.002307996,0.04211934,0.002872974,0.0006292429,0.001558673,0.004406,0.005297663,0.007329305,0.02844549,0.06105655],"study_design_scores_gemma":[0.8700918,0.06277187,0.004657236,0.006419013,0.001100054,0.0001453712,0.0003275613,0.003255903,0.00179005,0.003976491,0.04524065,0.0002239349],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.0004442575,0.00005551413,0.0004989135,0.00005393206,0.00009903942,0.9984469,0.0002076976,0.00002877976,0.0001650768],"genre_scores_gemma":[0.000554151,0.00004131983,0.001086131,0.00004971609,0.00001750354,0.9981285,0.00003339981,0.000001852729,0.00008754001],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.06560393,"threshold_uncertainty_score":0.3244016,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.166426845439749,"score_gpt":0.5087815799521503,"score_spread":0.3423547345124013,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}