{"id":"W2970372019","doi":"10.1007/978-3-030-14792-1_18","title":"The Role of Protein Lysine Methylation in the Regulation of Protein Function: Looking Beyond the Histone Code","year":2019,"lang":"en","type":"book-chapter","venue":"RNA technologies","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Carleton University","funders":"","keywords":"Histone code; Lysine; Histone methyltransferase; Histone; EZH2; Protein methylation; Code (set theory); Cell biology; Computational biology; Biology; Methylation; Genetics; Computer science; Methyltransferase; DNA; Programming language; Amino acid; Nucleosome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002697365,0.0004798124,0.0005827192,0.0004036629,0.0003674879,0.001510401,0.0007492194,0.0009083776,0.00426378],"category_scores_gemma":[0.0001859692,0.0002857658,0.0002843056,0.0006502313,0.001499239,0.002411325,0.0004976255,0.00227028,0.002849211],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007685284,"about_ca_system_score_gemma":0.0003645965,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005388272,"about_ca_topic_score_gemma":0.001051276,"domain_scores_codex":[0.9999086,0.00001174355,0.000003478396,0.00002774218,0.00003776932,0.00001071391],"domain_scores_gemma":[0.9999142,0.00005706675,0.000006071784,0.000006892192,0.000008036217,0.000007783636],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001253486,0.00006808926,0.0001834667,0.001236965,0.00003071767,0.0003058449,0.0005163031,0.001639362,0.1719407,0.4259195,0.03788309,0.3601506],"study_design_scores_gemma":[0.000009589452,0.00009054791,0.0005076912,0.0001862544,0.00001944378,0.0004927827,0.000150184,0.001347411,0.0423331,0.1493941,0.8054307,0.00003822802],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.008474175,0.7373854,0.05902567,0.008982245,0.005382107,0.00003080417,0.0001960969,0.0003961465,0.1801275],"genre_scores_gemma":[0.07886094,0.5768949,0.03697428,0.005263002,0.003251669,0.0001058612,0.0002397087,0.0002755899,0.2981341],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00426378,"threshold_uncertainty_score":0.01426381,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006687846442190653,"score_gpt":0.2194847675126494,"score_spread":0.2127969210704587,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}