{"id":"W2970375260","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2152","title":"Improved Expansion of Primary Normal and Cystic Fibrosis Human Airway Epithelial Cells Using PneumaCult™-Ex Plus, a Novel BPE- and Feeder-Free Medium That Promotes Maintenance of Their Mucociliary Differentiation Potential in Later Passages","year":2019,"lang":"en","type":"article","venue":"","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Stemcell Technologies","funders":"","keywords":"Cystic fibrosis; Mucociliary clearance; Airway; Cell biology; Pathology; Biology; Anatomy; Chemistry; Medicine; Internal medicine; Anesthesia; Lung","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003569133,0.0003015084,0.0003669917,0.0002325757,0.000229163,0.0003088462,0.0003274516,0.0002867302,0.001237451],"category_scores_gemma":[0.0001833923,0.0001178037,0.0003013555,0.0001914713,0.0001338104,0.0002284428,0.0004086893,0.0006791523,0.000702226],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001810148,"about_ca_system_score_gemma":0.0002914345,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00136995,"about_ca_topic_score_gemma":0.002516516,"domain_scores_codex":[0.9998078,0.00002081239,0.00003288022,0.0000291679,0.00007898297,0.00003040535],"domain_scores_gemma":[0.9998881,0.00002340545,0.000008044602,0.00001909816,0.0000319531,0.0000295406],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006916737,0.00002756133,0.0001235686,0.00003840463,0.000001800527,0.0000737076,0.00003397102,0.00004903191,0.9970359,0.00009022865,0.0001259922,0.002330681],"study_design_scores_gemma":[0.00001321983,0.0002094153,0.005370284,0.00001619197,0.00002001339,0.0006802778,0.00002498758,0.001019711,0.9794601,0.0000439644,0.01313382,0.000008073365],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9384958,0.006817381,0.04157645,0.0003437036,0.0003206064,0.0003317599,0.003004445,0.0005223965,0.008587495],"genre_scores_gemma":[0.9232661,0.003859535,0.0447408,0.0001681233,0.00007870698,0.000262034,0.006956998,0.0001246812,0.02054304],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00136995,"threshold_uncertainty_score":0.004139662,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01295328651076025,"score_gpt":0.2438625620726903,"score_spread":0.2309092755619301,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}