{"id":"W2970460758","doi":"10.1002/dvdy.110","title":"Nonlinear gene expression‐phenotype relationships contribute to variation and clefting in the A/WySn mouse","year":2019,"lang":"en","type":"article","venue":"Developmental Dynamics","topic":"Cleft Lip and Palate Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Alberta Children's Hospital; Alberta Bone and Joint Health Institute; University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; National Institute of Dental and Craniofacial Research; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Biology; Phenotype; Genetics; Gene; Variation (astronomy); Expression (computer science); Gene expression; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004547817,0.00008112166,0.00007035922,0.00004211019,0.00009218963,0.00003584972,0.0001198452,0.00009008663,0.00001048162],"category_scores_gemma":[0.0001083532,0.00006636066,0.00001514247,0.000112901,0.00001308106,0.000005558749,0.0001195081,0.000127818,0.00003791124],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003931054,"about_ca_system_score_gemma":0.00005286002,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002623078,"about_ca_topic_score_gemma":0.0002065143,"domain_scores_codex":[0.9992675,0.00008203198,0.0001485205,0.0002015222,0.0001298144,0.0001705683],"domain_scores_gemma":[0.9997188,0.00004409693,0.00002845424,0.0001268564,0.00003516096,0.00004659627],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00009370351,0.00005871746,0.4757206,0.00001873918,0.00001858098,0.000003031913,0.001468895,0.0002535149,0.5205275,0.0002809753,0.0001063373,0.001449394],"study_design_scores_gemma":[0.001189359,0.0001237212,0.9585298,0.00003739167,0.000005798768,0.00002566203,0.001196478,0.01125694,0.02290829,0.0001127681,0.004240146,0.0003736491],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997351,0.00002016155,0.001327114,0.0002262209,0.00004649963,0.0002937142,0.00003513217,0.000005124433,0.0006950456],"genre_scores_gemma":[0.9910856,0.00004011713,0.007635058,0.0002061612,0.00003665947,0.00001286575,0.000499812,0.00001109563,0.0004725856],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4976192,"threshold_uncertainty_score":0.2706109,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01343779147530532,"score_gpt":0.2527171810802386,"score_spread":0.2392793896049332,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}