{"id":"W2970485443","doi":"10.1139/cjpp-2019-0085","title":"Cardioprotective effects of (<i>E</i>)-4-hydroxy-N′-(1-(3-oxo-3H-benzo[f]chromen-2-yl)ethylidene)benzohydrazide: a newly synthesized coumarin hydrazone against isoproterenol-induced myocardial infarction in a rat model","year":2019,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Traditional Chinese Medicine Analysis","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Myocardial infarction; Histopathology; Creatine kinase; Medicine; Lactate dehydrogenase; QT interval; Cardiotoxicity; Chemistry; Heart rate; Internal medicine; Pharmacology; Coumarin; Endocrinology; Toxicity; Biochemistry; Enzyme; Pathology; Blood pressure","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009859127,0.0003501419,0.0002688955,0.0001679785,0.000109293,0.0001096142,0.000167539,0.0002419206,0.001066967],"category_scores_gemma":[0.00007612869,0.0001163581,0.0001875515,0.00008735868,0.00015207,0.0002110862,0.0001185749,0.0004651503,0.0002163439],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008541049,"about_ca_system_score_gemma":0.0001675899,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000303479,"about_ca_topic_score_gemma":0.0005766941,"domain_scores_codex":[0.9999573,0.00000647603,0.000004120127,0.000007969567,0.000009482398,0.00001456997],"domain_scores_gemma":[0.999926,0.000006010177,0.00003009517,0.000006303852,0.00001017939,0.00002148984],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000636206,0.0001421187,0.0001871905,0.00008119828,0.00001015275,0.00006520421,0.00000955334,0.00004057303,0.9963624,0.00003321424,0.00003489078,0.002397453],"study_design_scores_gemma":[0.000145097,0.005015317,0.007535136,0.00001074842,0.00004837272,0.0003428892,0.00002728288,0.0003105181,0.9852633,0.00002337372,0.001269698,0.000008250938],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950252,0.002527172,0.001188339,0.0001141203,0.00003565135,0.00003176721,0.0001378671,0.00005946271,0.0008802802],"genre_scores_gemma":[0.9946731,0.002193592,0.001514804,0.00006449754,0.00002777149,0.00002266008,0.0002668888,0.000005845036,0.001230966],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001066967,"threshold_uncertainty_score":0.003569305,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008998484763689526,"score_gpt":0.2480929001742014,"score_spread":0.2390944154105119,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}