{"id":"W2970496886","doi":"10.1016/j.bbi.2019.08.190","title":"miR-200a-3p modulates gene expression in comorbid pain and depression: Molecular implication for central sensitization","year":2019,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Stress Responses and Cortisol","field":"Neuroscience","cited_by":49,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Health Research Institutes; Ministry of Science and Technology, Taiwan; China Medical University, Taiwan; Cancer Research Society","keywords":"Chronic pain; SNi; Sensitization; Chronic stress; Prefrontal cortex; microRNA; Depression (economics); Medicine; Epigenetics; Neuroscience; Psychology; Bioinformatics; Internal medicine; Biology; Gene; Cognition","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001123654,0.0002124609,0.0002873512,0.0002046573,0.0003469918,0.0004919494,0.0001591343,0.0003177904,0.002070722],"category_scores_gemma":[0.0003745483,0.0002233274,0.0002906481,0.0001501014,0.0002478675,0.0001474447,0.0002640351,0.0006122161,0.0002893523],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003038209,"about_ca_system_score_gemma":0.0002964462,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001196791,"about_ca_topic_score_gemma":0.00232764,"domain_scores_codex":[0.9998573,0.00002380324,0.000009413427,0.00003633897,0.00002977492,0.00004333621],"domain_scores_gemma":[0.999897,0.0000191046,0.00003894933,0.000007854558,0.00001443568,0.00002265397],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004898363,0.0002504029,0.02429131,0.0002496513,0.0002394414,0.0006974787,0.0002292533,0.0002904029,0.9406549,0.001067817,0.001340086,0.02579088],"study_design_scores_gemma":[0.0006677385,0.001469985,0.7549708,0.0001414878,0.0008845208,0.003012523,0.0009240302,0.007616064,0.2136332,0.002489944,0.01412183,0.00006783925],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905834,0.002797361,0.001925243,0.0004686734,0.0001331098,0.0000382192,0.0008173349,0.00008475857,0.003151992],"genre_scores_gemma":[0.9967754,0.0004712941,0.0009515256,0.000203769,0.00002169847,0.00004493225,0.0002786996,0.00002075785,0.001231874],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002070722,"threshold_uncertainty_score":0.006927252,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01847917557525527,"score_gpt":0.2766177985759671,"score_spread":0.2581386230007118,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}