{"id":"W2970724440","doi":"10.1242/jcs.232991","title":"Differential nanoscale organisation of LFA-1 modulates T-cell migration","year":2019,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"H2020 European Research Council; National Institutes of Health; King's College London; Wellcome Trust; Guy's and St Thomas' Charity; Versus Arthritis; Arthritis Research UK; McGill University; Gordon and Betty Moore Foundation","keywords":"Biology; Cell biology; Integrin; Intracellular; Actin; Actin cytoskeleton; Focal adhesion; Cell adhesion; Effector; Cytoskeleton; Cell; Signal transduction; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007207452,0.00009655196,0.0001523352,0.0001198306,0.0001603113,0.00036205,0.00009769546,0.0002462199,0.0008735949],"category_scores_gemma":[0.0002015206,0.00008327539,0.0000914749,0.000100645,0.0001386069,0.000241147,0.0001330597,0.0002986621,0.0001821968],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002631625,"about_ca_system_score_gemma":0.0001034162,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003148984,"about_ca_topic_score_gemma":0.0004252236,"domain_scores_codex":[0.9998978,0.00001297287,0.000004743402,0.00001994778,0.00002062583,0.00004379178],"domain_scores_gemma":[0.9999403,0.0000138672,0.00001552143,0.000004726742,0.000009544749,0.00001614134],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004122612,0.000006668016,0.0001526034,0.00001185135,0.000001067596,0.000008131635,0.00001007321,0.00003943707,0.9989001,0.00004404926,0.00001801683,0.0007668837],"study_design_scores_gemma":[0.00001464178,0.0001867397,0.01862971,0.000009064518,0.0000158417,0.00008982256,0.0001038266,0.002776217,0.9766603,0.0001318192,0.001375368,0.000006715742],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978212,0.0004535808,0.0009527056,0.00004549037,0.00001305812,0.000005263252,0.00004277571,0.00002125053,0.0006446209],"genre_scores_gemma":[0.9988218,0.0002220177,0.000493969,0.00002670904,0.000005545027,0.00001123148,0.00003348126,0.000006286498,0.0003788779],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008735949,"threshold_uncertainty_score":0.002922475,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01033374319240716,"score_gpt":0.2684402289266761,"score_spread":0.2581064857342689,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}