{"id":"W2970728886","doi":"10.4049/jimmunol.1900136","title":"Combination of Modified NS1 and NS3 as a Novel Vaccine Strategy against Dengue Virus Infection","year":2019,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Mosquito-borne diseases and control","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"","keywords":"Dengue virus; Dengue vaccine; NS3; Virology; Dengue fever; Biology; Epitope; Immune system; Cytotoxic T cell; Virus; Immunization; Antigen; Immunology; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001179317,0.0004953541,0.0003742051,0.0002146576,0.0001279191,0.0002211004,0.0002962239,0.0003241487,0.0006682678],"category_scores_gemma":[0.00005967619,0.0001311858,0.0003539418,0.0001346428,0.0001493255,0.000248271,0.0002045005,0.000498934,0.0001682766],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002817766,"about_ca_system_score_gemma":0.000173236,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004911646,"about_ca_topic_score_gemma":0.0007562307,"domain_scores_codex":[0.9999163,0.00001139383,0.000007136022,0.00001466307,0.00002470017,0.00002580043],"domain_scores_gemma":[0.9999748,0.000002172193,0.000006899995,0.0000024868,0.000004710075,0.000008826996],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001742536,0.0001269151,0.0001260014,0.00008551771,0.00001767791,0.00004485675,0.00000951548,0.0004162948,0.9949536,0.0001539977,0.00007174175,0.003819652],"study_design_scores_gemma":[0.0001246428,0.003347842,0.002754754,0.00001676648,0.0001397118,0.0003749819,0.00002750511,0.004049589,0.9814855,0.0001591718,0.007502579,0.00001703937],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990566,0.002720982,0.005110092,0.000149558,0.00009507716,0.00007981829,0.0001680272,0.00007785442,0.001032671],"genre_scores_gemma":[0.9928558,0.001523765,0.003910427,0.00009307573,0.0000225663,0.00004821279,0.0002477158,0.00001120814,0.001287165],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006682678,"threshold_uncertainty_score":0.002235532,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01028200900057963,"score_gpt":0.2589735245336145,"score_spread":0.2486915155330349,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}