{"id":"W2970820653","doi":"10.1111/bjd.18469","title":"Efficacy and safety of topical delgocitinib in patients with chronic hand eczema: data from a randomized, double‐blind, vehicle‐controlled phase <scp>II</scp> a study","year":2019,"lang":"en","type":"article","venue":"British Journal of Dermatology","topic":"Contact Dermatitis and Allergies","field":"Medicine","cited_by":104,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"LEO Pharma; LEO Pharma Research Foundation","keywords":"Medicine; Discontinuation; Adverse effect; Randomized controlled trial; Confidence interval; Clinical endpoint; Internal medicine; Odds ratio; Statistical significance; Incidence (geometry); Clinical trial; Severity of illness; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002821239,0.0008219707,0.002673658,0.0002944261,0.0003727834,0.0008388762,0.000538627,0.001392712,0.004000793],"category_scores_gemma":[0.002166452,0.0004480465,0.002063768,0.0004019364,0.000871081,0.0007905923,0.0002607283,0.00176935,0.0006150277],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004329826,"about_ca_system_score_gemma":0.0008082038,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004788611,"about_ca_topic_score_gemma":0.001033274,"domain_scores_codex":[0.9987898,0.0006378123,0.0001459614,0.0001579586,0.0001482657,0.000120237],"domain_scores_gemma":[0.9973097,0.0009391726,0.0008620337,0.0002046307,0.0002085072,0.0004759291],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9360955,0.008595961,0.003904109,0.001556256,0.003017016,0.0000603991,0.00006731108,0.0003268222,0.007603012,0.00006330851,0.0007600891,0.03795033],"study_design_scores_gemma":[0.8850735,0.101425,0.01034037,0.00006400212,0.001385565,0.00009948765,0.00002369368,0.0002643692,0.0006472862,0.00004834434,0.0006114404,0.0000170333],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9872044,0.008301468,0.0005051409,0.0003171258,0.0001436052,0.001605703,0.0008938291,0.00005502815,0.0009735978],"genre_scores_gemma":[0.9926053,0.003486722,0.0007099098,0.0004739044,0.0002491614,0.001080231,0.0007757853,0.00001336052,0.0006054506],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004000793,"threshold_uncertainty_score":0.01492029,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01541033419864577,"score_gpt":0.2786165033381112,"score_spread":0.2632061691394654,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}