{"id":"W2970897351","doi":"10.3390/cells8091006","title":"Rac1 S71 Mediates the Interaction between Rac1 and 14-3-3 Proteins","year":2019,"lang":"en","type":"article","venue":"Cells","topic":"14-3-3 protein interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health","keywords":"RAC1; Phosphorylation; Cell biology; Immunoprecipitation; Signal transduction; Biology; HEK 293 cells; Protein kinase B; Protein–protein interaction; Chemistry; Biochemistry; Receptor; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001275301,0.0004332435,0.0002506253,0.0003307828,0.0004860261,0.0003381984,0.0003001644,0.0003151486,0.002582184],"category_scores_gemma":[0.0001262319,0.0002070483,0.0007288967,0.0001685285,0.0002070067,0.0001968574,0.0003836453,0.000465805,0.00116014],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006142881,"about_ca_system_score_gemma":0.0004052876,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001721643,"about_ca_topic_score_gemma":0.002191894,"domain_scores_codex":[0.9996852,0.00004057493,0.00001420986,0.00006122957,0.00007295607,0.00012596],"domain_scores_gemma":[0.9998744,0.0000136423,0.00003695409,0.00001285144,0.0000228622,0.00003929509],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008720843,0.00004676361,0.0007045529,0.00003472506,0.000009590644,0.00006828083,0.00001451986,0.00008936715,0.9966377,0.0003265546,0.0001081862,0.001872492],"study_design_scores_gemma":[0.00001204758,0.0001181131,0.0166756,0.00001354927,0.00001527801,0.0003494177,0.00003363191,0.003220524,0.9736732,0.0001433209,0.005733522,0.00001181564],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928111,0.001534051,0.002237697,0.0001578319,0.00003080778,0.00001611355,0.000157052,0.00006833668,0.002986952],"genre_scores_gemma":[0.9942577,0.0004861285,0.001369341,0.00005419482,0.000008702253,0.00001379789,0.0004781951,0.00001388906,0.003318088],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002582184,"threshold_uncertainty_score":0.008638322,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007887032790246043,"score_gpt":0.247446382228648,"score_spread":0.2395593494384019,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}