{"id":"W2970897351","doi":"10.3390/cells8091006","title":"Rac1 S71 Mediates the Interaction between Rac1 and 14-3-3 Proteins","year":2019,"lang":"en","type":"article","venue":"Cells","topic":"14-3-3 protein interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health","keywords":"RAC1; Phosphorylation; Cell biology; Immunoprecipitation; Signal transduction; Biology; HEK 293 cells; Protein kinase B; Protein–protein interaction; Chemistry; Biochemistry; Receptor; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001608895,0.0001293904,0.0001117182,0.00003046917,0.00008299599,0.00005260999,0.0001649211,0.0001199973,0.0001594937],"category_scores_gemma":[0.00006667282,0.00009622134,0.00006030094,0.00005267864,0.00006106536,0.00001028842,0.000130279,0.0001842667,0.0003485829],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001398973,"about_ca_system_score_gemma":0.00002797297,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003784482,"about_ca_topic_score_gemma":0.00001564843,"domain_scores_codex":[0.9992134,0.00007052434,0.0001613271,0.0002792909,0.00009768064,0.0001777579],"domain_scores_gemma":[0.9993597,0.00005827004,0.0000947303,0.0003683775,0.00006277778,0.00005619769],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002993696,0.00002370802,0.004121121,0.00001962476,0.00005615324,7.28338e-7,0.0001096406,0.00001465986,0.9883127,0.00001956088,0.003929991,0.003362209],"study_design_scores_gemma":[0.0002444737,0.0001423308,0.002083844,0.00001887297,0.00001906469,0.00000782688,0.0001544585,0.00002416724,0.806035,0.00008700757,0.191055,0.0001279791],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943433,0.0003298598,0.0003743508,0.0006220611,0.0005585388,0.0006330037,0.00001832205,0.00001825071,0.00310226],"genre_scores_gemma":[0.9938331,0.0001047069,0.0002977909,0.0001871701,0.0004617913,0.0000633899,0.00005755813,0.00002300673,0.004971443],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.187125,"threshold_uncertainty_score":0.4480444,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007887032790246043,"score_gpt":0.247446382228648,"score_spread":0.2395593494384019,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}