{"id":"W2970947655","doi":"10.1002/em.22327","title":"A Return to the Origin of the EMGS: Rejuvenating the Quest for Human Germ Cell Mutagens and Determining the Risk to Future Generations","year":2019,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada","funders":"Health Canada","keywords":"Biology; Genomics; Offspring; Germ cell; Mutagenesis; Mutagen; Genetics; Evolutionary biology; Computational biology; Genome; Mutation; Gene; Carcinogen; Pregnancy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003928295,0.0001602668,0.0001094133,0.00001909535,0.0005517771,0.000055794,0.0003506017,0.00007149084,0.000009628025],"category_scores_gemma":[0.00002397962,0.00007854487,0.0001021246,0.00006040191,0.0001091883,0.000004559809,0.0004485896,0.0001054588,0.000005539302],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001683423,"about_ca_system_score_gemma":0.00001925491,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000295899,"about_ca_topic_score_gemma":0.00008087394,"domain_scores_codex":[0.998842,0.0001999,0.0001758257,0.0003485906,0.0002055676,0.0002281088],"domain_scores_gemma":[0.9992367,0.00003900882,0.00009382999,0.0005515852,0.00001230846,0.00006658391],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001491798,0.00002287837,0.008267319,0.00001322054,0.00003495262,7.090025e-7,0.0005011804,0.0002826566,0.9891328,0.00002218792,0.0002381271,0.001469028],"study_design_scores_gemma":[0.0005211699,0.0003405844,0.04831802,0.00001349147,0.00009613701,0.00001242424,0.001757777,0.0002749766,0.8624498,0.00002305684,0.08595031,0.0002422683],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958087,0.0008075034,0.0005495687,0.001361247,0.00008326257,0.001169409,0.00009834552,0.000002808313,0.000119167],"genre_scores_gemma":[0.9975448,0.00016118,0.0002960094,0.0009164893,0.0001261258,0.0001209127,0.00002847075,0.00002740932,0.0007785708],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.126683,"threshold_uncertainty_score":0.4243879,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005624073486187423,"score_gpt":0.2297632347687991,"score_spread":0.2241391612826117,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}