{"id":"W2970947655","doi":"10.1002/em.22327","title":"A Return to the Origin of the EMGS: Rejuvenating the Quest for Human Germ Cell Mutagens and Determining the Risk to Future Generations","year":2019,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada","funders":"Health Canada","keywords":"Biology; Genomics; Offspring; Germ cell; Mutagenesis; Mutagen; Genetics; Evolutionary biology; Computational biology; Genome; Mutation; Gene; Carcinogen; Pregnancy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01870292,0.0009449521,0.001689559,0.001394973,0.002947742,0.005850052,0.002129261,0.009191735,0.005869833],"category_scores_gemma":[0.02498286,0.0006186477,0.001323089,0.0007260065,0.0139354,0.01304043,0.005124789,0.0229581,0.003051224],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002561319,"about_ca_system_score_gemma":0.005789206,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003157687,"about_ca_topic_score_gemma":0.004572601,"domain_scores_codex":[0.9940562,0.002379892,0.0003449126,0.001006764,0.001701676,0.000510529],"domain_scores_gemma":[0.9706829,0.01429488,0.001164777,0.003146088,0.006410732,0.004300634],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005869403,0.0003295097,0.006772439,0.0016332,0.0002456359,0.001406034,0.005800155,0.0006059187,0.009510988,0.1083978,0.4989146,0.3657967],"study_design_scores_gemma":[0.00005625936,0.0003310206,0.001975643,0.0009171336,0.00009694453,0.001354685,0.002800135,0.0003037039,0.003804796,0.08942001,0.8988388,0.0001008714],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.00495758,0.09688216,0.009301011,0.8603843,0.02440429,0.00002279091,0.0001326113,0.0003025758,0.003612629],"genre_scores_gemma":[0.07004534,0.1342292,0.0247409,0.7135513,0.03129464,0.00009776499,0.0002815158,0.0007361745,0.02502313],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01870292,"threshold_uncertainty_score":0.09891164,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005624073486187423,"score_gpt":0.2297632347687991,"score_spread":0.2241391612826117,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}