{"id":"W2970966292","doi":"10.14785/lymphosign-2019-0011","title":"New considerations in hematopoietic stem cell transplantation for severe combined immunodeficiency: how did newborn screening change our field, and can we finally brake the glass ceiling for haploidentical transplantation?","year":2019,"lang":"en","type":"article","venue":"LymphoSign Journal","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Transplantation; Hematopoietic stem cell transplantation; Severe combined immunodeficiency; Stem cell; Newborn screening; Disease; Intensive care medicine; Immunology; Pediatrics; Surgery; Internal medicine; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02326619,0.0009251932,0.001751618,0.001467804,0.002329246,0.004547005,0.002836264,0.01118009,0.006729776],"category_scores_gemma":[0.03564876,0.0004419201,0.001441052,0.0008669408,0.01126011,0.01558592,0.003213196,0.02019671,0.003028225],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004106818,"about_ca_system_score_gemma":0.007363905,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006182434,"about_ca_topic_score_gemma":0.01035241,"domain_scores_codex":[0.9936392,0.002871659,0.0006233088,0.0008251485,0.001478492,0.000562218],"domain_scores_gemma":[0.9686896,0.0185822,0.001173223,0.000792224,0.005910027,0.004852729],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004059809,0.0002345325,0.002744397,0.002549883,0.0001301746,0.00190643,0.001166523,0.0006613827,0.001025361,0.0483801,0.4300954,0.5106997],"study_design_scores_gemma":[0.00009655529,0.0004265478,0.002829864,0.00528047,0.0001289772,0.003592165,0.003405557,0.0006562342,0.0004529279,0.07623273,0.9067004,0.0001975775],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"review","genre_scores_codex":[0.0008963372,0.2534326,0.002099338,0.72581,0.01525913,0.00001189535,0.00005951032,0.00008448948,0.002346795],"genre_scores_gemma":[0.02904752,0.4519805,0.008968409,0.4381621,0.06544046,0.0001062167,0.0002047288,0.0001783772,0.005911674],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.02326619,"threshold_uncertainty_score":0.1230448,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01832097053543886,"score_gpt":0.2336855244946848,"score_spread":0.215364553959246,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}