{"id":"W2971053411","doi":"10.1182/blood-2018-99-119438","title":"In Vitro Activity and Target Modulation of PV-10 Against Relapsed and Refractory Pediatric Leukemia","year":2018,"lang":"en","type":"article","venue":"Blood","topic":"Cancer therapeutics and mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"","keywords":"Medicine; Leukemia; Oncology; Internal medicine; Transplantation; Pediatric cancer; Myeloid leukemia; Cancer; Refractory (planetary science); Acute leukemia; Cancer research; Immunology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000227214,0.0002753736,0.0002839529,0.000186517,0.000112226,0.0002056655,0.0002720817,0.0001814268,0.001339662],"category_scores_gemma":[0.000165195,0.00008036763,0.0002100741,0.0002670188,0.0001052656,0.0001077838,0.0001406964,0.0004179472,0.000402561],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002103343,"about_ca_system_score_gemma":0.0002306012,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007432225,"about_ca_topic_score_gemma":0.0007594755,"domain_scores_codex":[0.9998546,0.00004497075,0.00001169275,0.00002205807,0.00003089077,0.00003586452],"domain_scores_gemma":[0.9998915,0.00003416368,0.00001611437,0.00001539757,0.00002065454,0.00002216257],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001145801,0.0007348561,0.002063562,0.0003691552,0.000049694,0.0001563376,0.00008100823,0.001270226,0.9795308,0.000143476,0.000667678,0.01378721],"study_design_scores_gemma":[0.0003562607,0.0156047,0.01292683,0.00004129094,0.0001406723,0.0009624546,0.000106343,0.002426345,0.9597321,0.00005992901,0.007631926,0.00001116295],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913993,0.00515313,0.001124516,0.00007551393,0.00005811928,0.00007422022,0.0006374893,0.00004575358,0.001431888],"genre_scores_gemma":[0.9932082,0.002860462,0.0009329102,0.00005860263,0.00003436684,0.00007261546,0.001931328,0.000008289447,0.0008932659],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001339662,"threshold_uncertainty_score":0.004481673,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007119541544815468,"score_gpt":0.2298396906626565,"score_spread":0.222720149117841,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}